HPLC Pumps

HPLC Pumps for Precise Flow and Pressure Control

Explore single piston, dual piston, and constant pressure pump options for reliable solvent delivery across analytical and preparative LC workflows.

HPLC Pump

HPLC Pump Categories

Explore HPLC pumps designed for consistent solvent delivery, pressure control, and dependable flow performance across a range of analytical and preparative liquid chromatography applications.

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HPLC Pumps for Reliable Flow and Pressure Control

HPLC pumps are one of the most important components in any liquid chromatography system because they control solvent delivery, flow stability, and operating pressure throughout the method. The right pump helps support retention time consistency, reproducible separations, and dependable day-to-day instrument performance across analytical, preparative, clinical, and fluid-metering workflows.

Chrom Tech is an authorized distributor for Teledyne SSI, a recognized manufacturer of precision-engineered positive-displacement piston pumps used in demanding chromatography applications. These pump platforms are designed to deliver accurate, repeatable solvent movement under a wide range of flow and pressure conditions, making them well suited for laboratories that need dependable performance and long service life.

This category includes single-piston, dual-piston, and constant pressure HPLC pump classes to support different method requirements. Single-piston models provide compact, efficient flow delivery for many routine and specialized applications. Dual-piston configurations help improve flow smoothness and are often selected for more demanding isocratic workflows. Constant pressure models are used where stable pressure control is critical to process performance.

Available options include multiple flow ranges, pressure capabilities, wetted material choices such as stainless steel, PEEK, and Hastelloy, and configurations designed for both lower-flow analytical work and higher-flow preparative applications. This range gives laboratories flexibility when selecting a pump based on solvent compatibility, target pressure, flow requirements, and overall system design.

The overview tables below summarize key HPLC pump classes by material options, flow range, flow accuracy, pressure limit, stroke volume, temperature jacket availability, operating mode, and overall dimensions. Use these comparisons to identify the best fit for your liquid chromatography workflow, whether you need compact single-piston delivery, smoother dual-piston isocratic performance, or constant pressure operation for specialized applications.

Single-Piston Pumps

Pump Class Material Options Flow Range (mL/min) Flow Accuracy Pressure Limit (psi) Stroke Volume (µL) Temp Jacket Pump Mode Dimensions / Weight
M1 Class Stainless Steel, PEEK 0.00 – 10.00 5% 2,500 25.1 No Constant Flow 5.6”H x 3”W x 10.6”D
(14.1 x 7.6 x 26.7 cm)
6.1 lbs. (2.7 kg)
M1 Class Stainless Steel 0.0 – 40.0 5% 500 100.5 No Constant Flow 5.6”H x 3”W x 10.6”D
(14.1 x 7.6 x 26.7 cm)
6.1 lbs. (2.7 kg)
M1 Class Stainless Steel 0.0 – 100.0 5% 250 226.2 No Constant Flow 5.6”H x 3”W x 10.6”D
(14.1 x 7.6 x 26.7 cm)
6.1 lbs. (2.7 kg)
MX Class Stainless Steel 0.00 – 10.00 2% 5,000 25.1 No Constant Flow 6.4”H x 7”W x 16”D
(16.1 x 17.8 x 40.6 cm)
14.2 lbs. (6.4 kg)
LS Class Stainless Steel, PEEK 0.000 – 5.000 2% 6,000 SS / 5,000 PEEK 25.1 No Constant Flow 6.4”H x 7”W x 16”D
(16.1 x 17.8 x 40.6 cm)
15.3 lbs. (6.9 kg)
LS Class Stainless Steel, PEEK 0.00 – 10.00 2% 6,000 SS / 5,000 PEEK 50.3 No Constant Flow 6.4”H x 7”W x 16”D
(16.1 x 17.8 x 40.6 cm)
15.3 lbs. (6.9 kg)
LS Class Stainless Steel, PEEK 0.0 – 40.0 2% 1,500 201.1 No Constant Flow 6.4”H x 7”W x 16”D
(16.1 x 17.8 x 40.6 cm)
15.3 lbs. (6.9 kg)

Dual-Piston and Constant Pressure Pumps

Pump Class Material Options Flow Range (mL/min) Flow Accuracy Pressure Limit (psi) Stroke Volume (µL) Temp Jacket Pump Mode Dimensions / Weight
LD Class Stainless Steel, PEEK 0.000 – 12.000 2% 6,000 SS / 5,000 PEEK 30.0 No Constant Flow 6.4”H x 10”W x 17.5”D
(16.1 x 25.1 x 44.3 cm)
21.3 lbs. (9.7 kg)
LD Class Stainless Steel, PEEK, Hastelloy 0.00 – 36.00 2% 6,000 SS / Hastelloy, 5,000 PEEK 62.8 No (SS, PEEK) / Yes (Hastelloy) Constant Flow 6.4”H x 10”W x 17.5”D
(16.1 x 25.1 x 44.3 cm)
21.3 lbs. (9.7 kg)
LD Class Stainless Steel, PEEK, Hastelloy 0.0 – 100.0 2% 1,500 251.4 No (SS, PEEK) / Yes (Hastelloy) Constant Flow 6.4”H x 10”W x 17.5”D
(16.1 x 25.1 x 44.3 cm)
21.3 lbs. (9.7 kg)
PR Class Stainless Steel, PEEK, Hastelloy 0.0 – 100.0 3% 4,000 251.4 No (SS, PEEK) / Yes (Hastelloy) Constant Flow 6.4”H x 10”W x 17.5”D
(16.1 x 25.1 x 44.3 cm)
24.2 lbs. (11.0 kg)
PR Class Stainless Steel, PEEK, Hastelloy 0.0 – 300.0 3% 1,000 565.6 No (SS, PEEK) / Yes (Hastelloy) Constant Flow 6.4”H x 10”W x 17.5”D
(16.1 x 25.1 x 44.3 cm)
24.2 lbs. (11.0 kg)
CP Class Stainless Steel 0.000 – 12.000 2% 18,000 31.4 No Constant Pressure 6.4”H x 10”W x 17.5”D
(16.1 x 25.1 x 44.3 cm)
21.3 lbs. (9.7 kg)
CP Class Stainless Steel, Hastelloy 0.00 – 24.00 2% 10,000 62.8 No (SS) / Yes (Hastelloy) Constant Pressure 6.4”H x 10”W x 17.5”D
(16.1 x 25.1 x 44.3 cm)
21.3 lbs. (9.7 kg)
CP Class Stainless Steel 0.0 – 100.0 2% 4,000 251.0 No Constant Pressure 6.4”H x 10”W x 17.5”D
(16.1 x 25.1 x 44.3 cm)
21.3 lbs. (9.7 kg)
HF Series Stainless Steel 0.0 – 300.0 5% 10,000 452.4 No Constant Flow / Constant Pressure 8.9”H x 13.9”W x 22.1”D
(22.6 x 35.3 x 56.1 cm)
49.2 lbs. (22.3 kg)
Key Definitions ▶
HPLC Pump
An HPLC pump is the component in a liquid chromatography system that moves solvent through the flow path at a controlled flow rate or pressure, helping support accurate and reproducible separations.
Single-Piston Pump
A single-piston pump uses one reciprocating piston to deliver solvent and is commonly used in compact HPLC systems where reliable constant flow performance is needed.
Dual-Piston Pump
A dual-piston pump uses two pistons to help deliver smoother, more consistent solvent flow, making it a common choice for demanding isocratic liquid chromatography applications.
Constant Flow
Constant flow refers to pump operation that maintains a set solvent flow rate during the run, even as system backpressure changes.
Constant Pressure
Constant pressure refers to pump operation that maintains a target pressure rather than a fixed flow rate, which can be useful in specialized LC and fluid-handling applications.
Positive-Displacement Pump
A positive-displacement pump moves a defined volume of liquid with each piston stroke, which helps provide accurate and repeatable solvent delivery in HPLC workflows.
Wetted Materials
Wetted materials are the pump head and flow path materials that contact the solvent, such as stainless steel, PEEK, or Hastelloy, and they are selected based on pressure needs and chemical compatibility.
Frequently Asked Questions ▶
What does an HPLC pump do?
An HPLC pump moves solvent through the liquid chromatography system at a controlled flow rate or pressure. This solvent delivery is essential for consistent retention times, stable separations, and reliable system performance.
What is the difference between single-piston and dual-piston HPLC pumps?
Single-piston HPLC pumps use one reciprocating piston and are often selected for compact, efficient solvent delivery. Dual-piston pumps use two pistons to help create smoother flow and are commonly chosen for more demanding isocratic liquid chromatography applications.
What is the difference between constant flow and constant pressure pumps?
A constant flow pump is designed to maintain a set flow rate even as backpressure changes. A constant pressure pump is designed to maintain a target pressure instead of a fixed flow rate, which can be useful in specialized LC and fluid-handling workflows.
How do I choose the right HPLC pump for my application?
The right HPLC pump depends on your required flow range, operating pressure, solvent compatibility, pump mode, and application type. Laboratories often compare pump class, wetted materials, stroke volume, and pressure capability when selecting the best fit for their system.
Why do wetted materials matter in an HPLC pump?
Wetted materials are the parts of the pump that come into contact with the solvent. Options such as stainless steel, PEEK, and Hastelloy are selected based on chemical compatibility, pressure requirements, and the demands of the liquid chromatography method.
Are Chrom Tech HPLC pumps suitable for analytical and preparative workflows?
Yes. Chrom Tech’s HPLC pump lineup includes pump classes designed for a range of analytical, clinical, preparative, and fluid-metering applications. Different models support different flow rates, pressure limits, and material options so laboratories can match the pump to their workflow requirements.