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Posted by Chrom Tech on 16th Oct 2025

Five Ways to Reduce Costs in Your Chromatography Workflow

How You Can Save Money in Your Chromatography Laboratory Chromatography delivers powerful analytical capabilities—but it can also bring high operational costs. From consumables and maintenance …

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Posted by Chrom Tech on 16th Oct 2025

Are Your Autosampler Vials Compromising Your Results?

Exploring the Impact of Vial Quality on HPLC and GC Performance In chromatography, precision instrumentation is only part of the equation for reliable results. The consumables you choose—includ …

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Posted by Chrom Tech on 16th Oct 2025

Revolutionizing Your Chromatography | The Power of Poroshell and more

Are you dealing with increasing backpressure from your HPLC column or wishing for UHPLC-level performance without upgrading your entire system? Choosing the right tools is critical—but navigati …

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Posted by Chrom Tech on 16th Oct 2025

Unlocking the Benefits of Agilent Bond Elut HLB SPE

Discover how Agilent Bond Elut HLB SPE products can transform your sample preparation workflow, improving efficiency, recovery, and reproducibility across a wide range of analytical applications. Und …

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Posted by Chrom Tech on 16th Oct 2025

Reduce PFAS Background Interference and Contamination

According to the EPA, per- and polyfluoroalkyl substances (PFAS) are persistent in both the environment and the human body, and prolonged exposure may lead to adverse health outcomes. Also referred t …

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Posted by Chrom Tech on 15th Oct 2025

Capillary Tubing Selection Guide for Agilent HPLC Systems

Replacing the capillary tubing connections in your HPLC system can feel like an overwhelming task, but Chrom Tech is here to simplify the process. Selecting the right tubing lengths, diameters, and c …

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Posted by Chrom Tech on 15th Oct 2025

Chromatography Identifies Clinical Classifiers of COVID-19

The COVID-19 pandemic has presented unprecedented global challenges due to its rapid transmission, diverse symptoms, and complex biological behavior. As researchers continue to study the virus, advan …

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Posted by Chrom Tech on 15th Oct 2025

Reverse-Phase Liquid Chromatography vs. Hydrophilic Interaction Liquid Chromatography

Liquid chromatography is one of the most widely used analytical techniques for separating complex mixtures. Among its most common approaches are Reverse-Phase Liquid Chromatography (RPLC) and Hydroph …

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Posted by Chrom Tech on 15th Oct 2025

The Role of Chromatography in Cannabis Testing

The use of cannabis in the United States continues to expand as more states legalize both medical and recreational consumption. With this growth, regulatory agencies have implemented mandatory testin …

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Posted by Chrom Tech on 15th Oct 2025

Offline vs. Online Degassing of HPLC Solvents

Gas bubbles and outgassing can significantly affect HPLC performance. Outgassing occurs when the dissolved gas concentration exceeds the solvent’s absorption capacity. Variables such as tempera …

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Posted by Chrom Tech on 15th Oct 2025

How To Make an HPLC Connection With PEEK Tubing

Making an HPLC Connection With PEEK Tubing Creating a proper HPLC connection is essential for ensuring leak-free performance and consistent chromatographic results. With PEEK (Polyetheretherketone) t …

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Posted by Chrom Tech on 15th Oct 2025

A Sneak Peak into the Largest HPLC Industry in the World - Biotechnology Applications

HPLC in Biotechnology: Advancing Analytical Precision Biotechnology is one of the world’s largest and most rapidly evolving industries, spanning applications in food and agriculture, pharmaceut …

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Posted by Chrom Tech on 15th Oct 2025

Inline Filters vs. Guard Columns for HPLC

Protecting Your HPLC Columns: The Role of Filters and Guard Columns In high-performance liquid chromatography (HPLC), filters such as inline filters, pre-column filters, and guard columns play an ess …

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Posted by Chrom Tech on 14th Oct 2025

Helpful Fluoropolymer Tubing Guide for Your HPLC Applications

What Types of Tubing Are Used in the Laboratory? In liquid chromatography and general laboratory fluidic systems, a wide range of tubing materials and configurations are available to meet specific ne …

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Posted by Chrom Tech on 14th Oct 2025

How Do You Dispose of HPLC Waste?

High-Performance Liquid Chromatography (HPLC) is an essential analytical technique used across industries to separate complex mixtures into individual components. Whether quantifying unknown analytes …

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Posted by Chrom Tech on 14th Oct 2025

An Essential Guide to HPLC Fittings for Your Laboratory

An Introduction to HPLC Fittings HPLC fittings play a vital role in chromatography systems, connecting tubing, adapters, and components to ensure leak-free, stable operation. Secure connections are c …

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Posted by Chrom Tech on 14th Oct 2025

How to Connect a Syringe to HPLC Tubing

In chromatography and LC applications, connecting a syringe to your pump for priming or maintenance is a common and essential task. Many labs have improvised solutions for this connection, but Chrom …

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Posted by Chrom Tech on 14th Oct 2025

Method Transfer between Poroshell and Zorbax HPLC Columns

Superficially porous particle (SPP) HPLC columns offer one of the most effective ways to achieve high chromatographic efficiency without the excessive backpressure typically associated with sub-2-&mu …

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Posted by Chrom Tech on 14th Oct 2025

How do Stainless-Steel Fittings Differ from Polymer-Based Fittings?

Both stainless-steel and polymer-based fittings are widely used in HPLC systems, each offering distinct advantages depending on the laboratory’s pressure requirements, sample type, and analytic …

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Posted by Chrom Tech on 14th Oct 2025

Revisiting ‘The Big Pain’

During the pandemic, drug testing laboratories faced unprecedented strain as resources shifted toward COVID-19 testing. This caused other forms of testing—such as routine employee drug screenin …

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Posted by Chrom Tech on 14th Oct 2025

Three Reasons You’ll Want to Switch to Agilent Capillary Tubing

Stainless steel tubing is the industry standard for HPLC and UHPLC systems due to its exceptional strength, solvent compatibility, and ability to withstand extremely high pressures. In contrast, PEEK …

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Posted by Chrom Tech on 14th Oct 2025

Safety Waste Compliance in One Easy Step

Improper waste collection and handling of hazardous materials can pose serious health and safety risks in any laboratory. While the days of disposing HPLC solvent waste down the drain are long gone, …

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Posted by Chrom Tech on 14th Oct 2025

What Sample Prep is Best for Vitamin D Analysis?

With growing demand for sensitive and specific analytical techniques, laboratories are increasingly focusing on accurate low-level detection of endogenous vitamins and hormones in biological samples. …

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Posted by Chrom Tech on 14th Oct 2025

What is the Smallest Sample Volume You Can Use in 96 Well Plates?

For high-throughput laboratories, 96-well plates have become a cornerstone of efficient sample handling. Compared to chromatography vials, they offer significant benefits in cost savings, automation …

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Posted by Chrom Tech on 14th Oct 2025

Should You Use a Glass Pre-Filter Syringe Filter?

Proper sample filtration is a key step in chromatography that directly impacts both analytical accuracy and instrument performance. High-quality filtration ensures consistent, reliable results while …

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Posted by Chrom Tech on 14th Oct 2025

How to Choose the Right Septa for Your Autosampler Vial Closure

When performing LC (Liquid Chromatography) or GC (Gas Chromatography) analyses, it’s important to store and transport samples in the right type of vial. Chromatography vials come in a variety o …

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Posted by Chrom Tech on 14th Oct 2025

How to Save Money and Increase Accuracy on Sample Prep

Automation can significantly enhance laboratory productivity by increasing throughput and precision in sample preparation. However, not every lab has the workload or budget for full automation. For t …

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Posted by Chrom Tech on 14th Oct 2025

EHS Compliance: Safely Manage HPLC Solvent Waste

Many solvents and samples used in high-performance liquid chromatography (HPLC) are flammable or hazardous. To protect your lab and personnel, proper HPLC solvent waste disposal is critical. Chrom Te …

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Posted by Chrom Tech on 14th Oct 2025

How Many Injections Can I Get on My HPLC Column?

It depends! Several factors influence how many injections you can perform on your HPLC column, including: Injecting “dirty” samples Following the operating conditions recommended by the …

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Posted by Chrom Tech on 14th Oct 2025

Should I Use a Guard Column

In any liquid chromatography (LC) system, the HPLC column is the heart of the separation process. It is here that analytes are isolated for both qualitative and quantitative analysis. While HPLC colu …

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Posted by Chrom Tech on 14th Oct 2025

Pore Size vs. Particle Size in HPLC Columns

Selecting the right HPLC column is crucial for achieving precise, reproducible chromatographic results. Chemical factors such as stationary phase type and pore size influence selectivity and retent …

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Posted by Chrom Tech on 7th Oct 2025

Syringe Filters for HPLC Sample Preparation: A Guide to Choosing the Right Filter for Consistent and Accurate Results

How to Choose the Right Syringe Filter for HPLC Sample Preparation Sample preparation is a critical step in high-performance liquid chromatography (HPLC). One of the most common techniques to ensure r …

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