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Posted by Chrom Tech on 16th Oct 2025

Five Ways to Reduce Costs in Your Chromatography Workflow

How You Can Save Money in Your Chromatography Laboratory Chromatography delivers powerful analytical capabilities—but it can also bring high operational costs. From consumables and maintenance …

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Posted by Chrom Tech on 16th Oct 2025

How to Cut HPLC Tubing: Your Guide to Peak Performance

High-performance liquid chromatography (HPLC) is one of the most powerful tools in analytical chemistry—but achieving precise, reproducible results depends on more than just the instrument itse …

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Posted by Chrom Tech on 16th Oct 2025

Revolutionizing Your Chromatography | The Power of Poroshell and more

Are you dealing with increasing backpressure from your HPLC column or wishing for UHPLC-level performance without upgrading your entire system? Choosing the right tools is critical—but navigati …

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Posted by Chrom Tech on 16th Oct 2025

Unlocking the Benefits of Agilent Bond Elut HLB SPE

Discover how Agilent Bond Elut HLB SPE products can transform your sample preparation workflow, improving efficiency, recovery, and reproducibility across a wide range of analytical applications. Und …

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Posted by Chrom Tech on 15th Oct 2025

Pesticide and Mycotoxin Analysis in Cannabis Brownies

Ensuring the safety of cannabis-derived edibles such as brownies requires precise and dependable analytical testing for both pesticides and mycotoxins. These contaminants pose potential health risks …

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Posted by Chrom Tech on 15th Oct 2025

To Cut or Not-to-Cut

When setting up an HPLC system, ensuring that tubing ends are flat, clean, and burr-free is essential for achieving accurate, reproducible results. A properly prepared connection minimizes dead volum …

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Posted by Chrom Tech on 15th Oct 2025

Which 96-Well Plate Should I Use for LCMS?

Choosing the right 96-well plate for LCMS applications depends on several critical factors: rim design, sample recovery needs, and potential for analyte binding to the plate material. Selecting the r …

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Posted by Chrom Tech on 15th Oct 2025

Reverse-Phase Liquid Chromatography vs. Hydrophilic Interaction Liquid Chromatography

Liquid chromatography is one of the most widely used analytical techniques for separating complex mixtures. Among its most common approaches are Reverse-Phase Liquid Chromatography (RPLC) and Hydroph …

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Posted by Chrom Tech on 15th Oct 2025

A Sneak Peak into the Largest HPLC Industry in the World - Biotechnology Applications

HPLC in Biotechnology: Advancing Analytical Precision Biotechnology is one of the world’s largest and most rapidly evolving industries, spanning applications in food and agriculture, pharmaceut …

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Posted by Chrom Tech on 15th Oct 2025

New and Dangerous Synthetic Opioids

Are New Synthetic Opioids Increasing Risks? Synthetic opioids are critical tools in modern medicine for managing severe pain. However, their extreme potency and addictive potential make them dangerou …

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Posted by Chrom Tech on 14th Oct 2025

An Essential Guide to HPLC Fittings for Your Laboratory

An Introduction to HPLC Fittings HPLC fittings play a vital role in chromatography systems, connecting tubing, adapters, and components to ensure leak-free, stable operation. Secure connections are c …

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Posted by Chrom Tech on 14th Oct 2025

How to Connect a Syringe to HPLC Tubing

In chromatography and LC applications, connecting a syringe to your pump for priming or maintenance is a common and essential task. Many labs have improvised solutions for this connection, but Chrom …

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Posted by Chrom Tech on 14th Oct 2025

How do Stainless-Steel Fittings Differ from Polymer-Based Fittings?

Both stainless-steel and polymer-based fittings are widely used in HPLC systems, each offering distinct advantages depending on the laboratory’s pressure requirements, sample type, and analytic …

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Posted by Chrom Tech on 14th Oct 2025

Using 96 Well Plates In High Throughput Laboratories

For high-throughput laboratories, switching from traditional autosampler vials to 96-well plates offers substantial advantages—particularly in automation, consistency, and time savings. While n …

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Posted by Chrom Tech on 14th Oct 2025

What LC Column Should I Use for EtG and EtS Detection?

Ethyl glucuronide (EtG) and ethyl sulfate (EtS) are direct metabolites of ethanol produced in the liver after alcohol consumption. These highly polar compounds are excellent biomarkers for recent alc …

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Posted by Chrom Tech on 14th Oct 2025

EHS Compliance: Safely Manage HPLC Solvent Waste

Many solvents and samples used in high-performance liquid chromatography (HPLC) are flammable or hazardous. To protect your lab and personnel, proper HPLC solvent waste disposal is critical. Chrom Te …

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Posted by Chrom Tech on 14th Oct 2025

Revolutionizing UHPLC Connections: Introducing MarvelXACT by IDEX

Reliable HPLC fittings are essential for achieving accurate and consistent results in UHPLC (Ultra-High Performance Liquid Chromatography). Improper fittings can lead to leaks, inconsistent data, and …

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Posted by Chrom Tech on 14th Oct 2025

How To Maximize HPLC Column Lifetime

All HPLC columns experience gradual wear over time. Factors such as sample injections, residual proteins, lipids, and particulates can accumulate inside the column, leading to increased backpressure …

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Posted by Chrom Tech on 14th Oct 2025

Should I Use a Guard Column

In any liquid chromatography (LC) system, the HPLC column is the heart of the separation process. It is here that analytes are isolated for both qualitative and quantitative analysis. While HPLC colu …

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Posted by Chrom Tech on 14th Oct 2025

Acetonitrile vs. Methanol for Reverse Phase Chromatography

Acetonitrile vs. Methanol in Reversed-Phase Chromatography Acetonitrile (ACN) and Methanol (MeOH) are the two most common organic modifiers used in reversed-phase HPLC. Each solvent exhibits unique …

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Posted by Chrom Tech on 14th Oct 2025

Pore Size vs. Particle Size in HPLC Columns

Selecting the right HPLC column is crucial for achieving precise, reproducible chromatographic results. Chemical factors such as stationary phase type and pore size influence selectivity and retent …

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Posted by Chrom Tech on 7th Oct 2025

Syringe Filters for HPLC Sample Preparation: A Guide to Choosing the Right Filter for Consistent and Accurate Results

How to Choose the Right Syringe Filter for HPLC Sample Preparation Sample preparation is a critical step in high-performance liquid chromatography (HPLC). One of the most common techniques to ensure r …

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