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To Cut or Not-to-Cut

Posted by Chrom Tech on 15th Oct 2025

To Cut or Not-to-Cut

When setting up an HPLC system, ensuring that tubing ends are flat, clean, and burr-free is essential for achieving accurate, reproducible results. A properly prepared connection minimizes dead volum …

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Which 96-Well Plate Should I Use for LCMS?

Posted by Chrom Tech on 15th Oct 2025

Which 96-Well Plate Should I Use for LCMS?

Choosing the right 96-well plate for LCMS applications depends on several critical factors: rim design, sample recovery needs, and potential for analyte binding to the plate material. Selecting the r …

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New and Dangerous Synthetic Opioids

Posted by Chrom Tech on 15th Oct 2025

New and Dangerous Synthetic Opioids

Are New Synthetic Opioids Increasing Risks? Synthetic opioids are critical tools in modern medicine for managing severe pain. However, their extreme potency and addictive potential make them dangerou …

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How to Connect a Syringe to HPLC Tubing

Posted by Chrom Tech on 14th Oct 2025

How to Connect a Syringe to HPLC Tubing

In chromatography and LC applications, connecting a syringe to your pump for priming or maintenance is a common and essential task. Many labs have improvised solutions for this connection, but Chrom …

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EHS Compliance: Safely Manage HPLC Solvent Waste

Posted by Chrom Tech on 14th Oct 2025

EHS Compliance: Safely Manage HPLC Solvent Waste

Many solvents and samples used in high-performance liquid chromatography (HPLC) are flammable or hazardous. To protect your lab and personnel, proper HPLC solvent waste disposal is critical. Chrom Te …

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How To Maximize HPLC Column Lifetime

Posted by Chrom Tech on 14th Oct 2025

How To Maximize HPLC Column Lifetime

All HPLC columns experience gradual wear over time. Factors such as sample injections, residual proteins, lipids, and particulates can accumulate inside the column, leading to increased backpressure …

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Should I Use a Guard Column

Posted by Chrom Tech on 14th Oct 2025

Should I Use a Guard Column

In any liquid chromatography (LC) system, the HPLC column is the heart of the separation process. It is here that analytes are isolated for both qualitative and quantitative analysis. While HPLC colu …

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Pore Size vs. Particle Size in HPLC Columns

Posted by Chrom Tech on 14th Oct 2025

Pore Size vs. Particle Size in HPLC Columns

Selecting the right HPLC column is crucial for achieving precise, reproducible chromatographic results. Chemical factors such as stationary phase type and pore size influence selectivity and retent …

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