Imtakt

Imtakt HPLC columns are engineered in Japan using proprietary silica and polymer chemistries that deliver exceptional peak symmetry, wide pH compatibility, and consistent batch-to-batch performance. Designed for high-efficiency separations, Imtakt phases support demanding pharmaceutical, biochemical, environmental, and LC-MS workflows.

The Imtakt column family spans a comprehensive range of selectivities and performance profiles:

  • Decapo DX-C18 — wide-pH reversed-phase development (pH 1–12) with excellent stability.
  • Presto FF-C18 — ultra-fast, high-resolution separations for high-throughput methods.
  • Cadenza CD-C18 — specialized for isomer, structural, and closely related compound separations.
  • Intrada — optimized for amino acids and organic acids, including LC/MS compatibility.
  • Scherzo C18 — multi-mode phase combining reversed-phase and ion-exchange interactions.

These advanced phases give analysts powerful tools for method development, impurity profiling, chiral-adjacent workflows, metabolite analysis, and challenging structural or polarity-rich separations.

For expert guidance on selecting the right Imtakt column for your method, contact Chrom Tech for tailored support and fast U.S. fulfillment.

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Key Definitions ▸
Wide-pH Reversed-Phase Operation
Operation across broad pH ranges—including acidic, neutral, and basic conditions—allowing flexible method development and enhanced control over retention and selectivity.
Multi-Mode Chromatography (MM)
A column design combining reversed-phase, anion-exchange, and cation-exchange interactions to provide multiple selectivity mechanisms in a single stationary phase—ideal for complex or co-eluting analytes.
High-Speed Chromatography
Rapid analyses enabled by low back-pressure, high-efficiency particle technologies designed to maintain resolution while significantly reducing run times.
Isomer & Structural Separations
Selectivity designed to resolve positional, geometric, and structural isomers by exploiting subtle steric and electronic differences between closely related molecules.
Amino Acid & Organic Acid Analysis
Specialized chemistries optimized for highly polar, zwitterionic, and small organic acids under HPLC or LC/MS conditions—supporting sensitive metabolite and protein-hydrolysate workflows.
Frequently Asked Questions ▸
What makes Imtakt HPLC columns unique?
Imtakt columns use proprietary silica and polymer chemistries that deliver fast equilibration, superior peak shapes, wide pH compatibility, and highly reproducible results—making them ideal for advanced method development and LC-MS workflows.
Which Imtakt column is best for amino acid analysis?
The Intrada Amino Acid column is specifically optimized for rapid, high-resolution separation of amino acids and organic acids under HPLC or LC/MS conditions, offering outstanding selectivity and sensitivity.
Can Imtakt columns operate under extreme pH or high-pressure conditions?
Yes. Columns such as Dacapo DX-C18 support pH 1–12, and all Imtakt phases are designed for robust mechanical and chemical stability under high-pressure HPLC and UHPLC operation.
Are Imtakt columns suitable for isomer or structural separations?
Yes. The Cadenza CD-C18 series excels at resolving positional, geometric, and structural isomers due to its finely tuned selectivity and proprietary bonding technology.