Well Plate Instrumentation

96-Well Microplate Instrumentation

Chrom Tech provides a comprehensive portfolio of 96-well microplate instrumentation engineered to improve efficiency, accuracy, and reproducibility across high-throughput laboratory workflows. Each system is built for precise control and seamless compatibility with Chrom Tech microplates, sealing solutions, and sample-prep accessories.

Our instrumentation lineup includes plate heat sealers for secure, evaporation-resistant sealing; positive pressure manifolds and vacuum processors for consistent filtration and SPE workflows; and high-performance Porvair evaporators designed to accelerate solvent removal without compromising sample integrity. These tools help laboratories eliminate manual bottlenecks, enhance throughput, and maintain reliable sample-to-sample uniformity.

The UltraSeal provides rapid, uniform thermal sealing across 96-well plates, preventing evaporation and cross-contamination during storage or incubation. For laboratories requiring high-efficiency evaporation, the Ultravap Mistral and related Porvair evaporators streamline solvent removal and concentrate samples quickly—ideal for LC/MS, SPE, and high-volume sample preparation environments.

Supported by Chrom Tech’s knowledgeable technical team and nationwide service capabilities, our 96-well instrumentation solutions help laboratories achieve consistent results, reduce operational costs, and scale their workflows with confidence.

Looking for More 96-Well Plate Options?

View the complete lineup of polypropylene, deep-well, glass-insert, and specialty plate formats.

Explore All 96-Well Plates

96-Well Microplate Instrumentation Categories

Explore a complete portfolio of 96-well microplate instrumentation engineered to improve efficiency.

Explore Well Plate Sealers

Well plate sealers

Protect samples from evaporation and contamination with reliable well plate sealing solutions for routine and high-throughput workflows.

Features
  • Cost-effective foil sealing solutions
  • Excellent adhesion
  • Withstands repeated microplate handling

Explore Cerex Positive Pressure Processor

Cerex positive pressure processor

Deliver smooth, immediate pressure and flow adjustments for consistent well-to-well processing in sample preparation workflows.

Features
  • Fine pressure and flow control
  • Provides uniform flow for extraction steps
  • Even pressure to each column

Explore Porvair Evaporators and Accessories

Porvair evaporators and accessories

Designed to quickly and efficiently dry down samples in well plates for concentration and LC/MS sample prep workflows.

Features
  • Robot compatible
  • Each method has 5 timed stages
  • Timed controls for temperature, gas flow, and needle depth
  • 15 password-protected methods
Key Definitions â–¸
Plate Heat Sealer
A benchtop instrument that applies uniform heat and pressure to microplates to bond sealing films or foils, preventing evaporation and contamination.
Positive Pressure Manifold
A device that uses controlled air pressure to drive liquid through SPE, filtration, or collection plates, improving uniformity compared to vacuum-based methods.
Vacuum Processor
An instrument that uses adjustable vacuum levels to pull samples through 96-well plates for extraction, filtration, or cleanup workflows.
Evaporator
A system designed to remove solvents from microplate wells using heat, gas flow, or controlled vacuum— essential for LC/MS sample prep and concentration steps.
Porvair Evaporator
A high-efficiency solvent evaporation platform from Porvair Sciences used for concentration and drying of samples in 96-well plate formats.
Thermal Sealing
The process of bonding a heat-activated film or foil to a microplate using controlled temperature and pressure for a uniform, long-lasting seal.
Frequently Asked Questions â–¸
What workflows benefit most from 96-well microplate instrumentation?
These instruments are ideal for high-throughput LC/MS prep, SPE, filtration, evaporation, PCR plate sealing, and automated multi-step workflows requiring speed, consistency, and low hands-on time.
Do heat sealers work with all 96-well plate materials?
Most heat sealers—including the UltraSeal—are compatible with polypropylene, polystyrene, and specialty coated plates, but the optimal sealing foil may vary by application.
When should I use a positive pressure manifold instead of vacuum?
Positive pressure provides more uniform well-to-well flow, especially for SPE and filtration plates where variable resistance can cause uneven processing under vacuum.
What advantages do Porvair evaporators offer for LC/MS workflows?
Porvair evaporators deliver fast, controlled solvent removal without overheating samples, helping concentrate analytes efficiently while preserving sample integrity.
Are these instruments compatible with Chrom Tech 96-well plates and seals?
Yes. All instruments offered by Chrom Tech are selected for compatibility with Chrom Tech 96-well plates, sealing foils, films, mats, and related sample prep accessories used in automated laboratory workflows.