Well Plate Instrumentation

96-Well Microplate Instrumentation

Chrom Tech provides a comprehensive portfolio of 96-well microplate instrumentation engineered to improve efficiency, accuracy, and reproducibility across high-throughput laboratory workflows. Each system is built for precise control and seamless compatibility with Chrom Tech microplates, sealing solutions, and sample-prep accessories.

Our instrumentation lineup includes plate heat sealers for secure, evaporation-resistant sealing; positive pressure manifolds and vacuum processors for consistent filtration and SPE workflows; and high-performance Porvair evaporators designed to accelerate solvent removal without compromising sample integrity. These tools help laboratories eliminate manual bottlenecks, enhance throughput, and maintain reliable sample-to-sample uniformity.

The UltraSeal provides rapid, uniform thermal sealing across 96-well plates, preventing evaporation and cross-contamination during storage or incubation. For laboratories requiring high-efficiency evaporation, the Ultravap Mistral and related Porvair evaporators streamline solvent removal and concentrate samples quickly—ideal for LC/MS, SPE, and high-volume sample preparation environments.

Supported by Chrom Tech’s knowledgeable technical team and nationwide service capabilities, our 96-well instrumentation solutions help laboratories achieve consistent results, reduce operational costs, and scale their workflows with confidence.

Looking for More 96-Well Plate Options?

View the complete lineup of polypropylene, deep-well, glass-insert, and specialty plate formats.

Explore All 96-Well Plates

96-Well Microplate Instrumentation Categories

Explore a complete portfolio of 96-well microplate instrumentation engineered to improve efficiency

Explore Well Plate Sealers

Protect your samples from evaporation and contamination sealing with cost-effective foil seals.

Features
  • Excellent adhesion
  • Withstands repeated microplate handling

Explore Cerex Positive Pressure Processor

Fine Pressure and Flow controls for smooth and immediate adjustments.

Features
  • Provides uniform flow for all extraction steps
  • Even pressure to each column

Explore Porvair Evaporators and Accessories

Designed to quickly and efficiently dry down samples in well plates

Features
  • Robot compatible
  • Each method has 5 timed stages
  • Timed stage controls: gas temperature, gas flow rate, needle depth
  • 15 password protected methods

Key Definitions

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Plate Heat Sealer
A benchtop instrument that applies uniform heat and pressure to microplates to bond sealing films or foils, preventing evaporation and contamination.
Positive Pressure Manifold
A device that uses controlled air pressure to drive liquid through SPE, filtration, or collection plates, improving uniformity compared to vacuum-based methods.
Vacuum Processor
An instrument that uses adjustable vacuum levels to pull samples through 96-well plates for extraction, filtration, or cleanup workflows.
Evaporator
A system designed to remove solvents from microplate wells using heat, gas flow, or controlled vacuum— essential for LC/MS sample prep and concentration steps.
Porvair Evaporator
A high-efficiency solvent evaporation platform from Porvair Sciences used for concentration and drying of samples in 96-well plate formats.
Thermal Sealing
The process of bonding a heat-activated film or foil to a microplate using controlled temperature and pressure for a uniform, long-lasting seal.

Frequently Asked Questions

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What workflows benefit most from 96-well microplate instrumentation?

These instruments are ideal for high-throughput LC/MS prep, SPE, filtration, evaporation, PCR plate sealing, and automated multi-step workflows requiring speed, consistency, and low hands-on time.

Do heat sealers work with all 96-well plate materials?

Most heat sealers—including the UltraSeal—are compatible with polypropylene, polystyrene, and specialty coated plates, but the optimal sealing foil may vary by application.

When should I use a positive pressure manifold instead of vacuum?

Positive pressure provides more uniform well-to-well flow, especially for SPE and filtration plates where variable resistance can cause uneven processing under vacuum.

What advantages do Porvair evaporators offer for LC/MS workflows?

Porvair evaporators deliver fast, controlled solvent removal without overheating samples, helping concentrate analytes efficiently while preserving sample integrity.

Are these instruments compatible with Chrom Tech 96-well plates and seals?

Yes. All instruments offered by Chrom Tech are selected for full compatibility w