Blog

20th Dec 2024

How to Connect a Syringe to HPLC Tubing

Connecting a syringe to your LC pump for tasks like priming the system (and other applications) is a common need. We've seen various inventive solutions in laboratories where people have connected the …

read more

20th Dec 2024

ASK BETHANY | Should I Use a Guard Column

HPLC ColumnsThe column is one of the most crucial components in an LC system, as it is where analytes are separated from a mixture for both qualitative and quantitative analysis. While HPLC colum …

read more

20th Dec 2024

ASK BEN | 4 Simple Steps to Find the Right GC Liner

We frequently receive questions about GC liners, particularly regarding which liner is best suited for a specific application. Selecting the right GC inlet liner is essential for proper sample analysi …

read more

20th Dec 2024

What are the Benefits of Glass Vials in the Laboratory?

Chromatography vials are compact glass or plastic containers utilized in laboratories to hold and transport samples until they are ready for analysis by HPLC or GC. If you're reading this, it's likely …

read more

19th Dec 2024

How to Properly Swage HPLC Fittings

Being able to properly change and connect fittings on an HPLC system is an essential skill for any chromatographer. At some point, you'll need to adjust or tighten a connection within your HPLC setup. …

read more

3rd Dec 2024

Environmental Applications of Chromatography

One of the most pressing concerns in today’s world is the state of our environment. Our planet faces numerous challenges, including climate change, deforestation, and ozone depletion. However, one of …

read more

3rd Dec 2024

How to Select Chromatography Vials

Several factors influence the choice of the best vial for your needs, including sample volatility, sample volume, and light sensitivity. Selecting the right vial is crucial for maximizing ROI, enhanci …

read more

3rd Dec 2024

Reverse-Phase Liquid Chromatography vs. Hydrophilic Interaction Liquid Chromatography

Liquid chromatography can be performed using various techniques, including reverse-phase and hydrophilic interaction liquid chromatography (HILIC). This method of chromatography involves an HPLC pump …

read more

3rd Dec 2024

Chromatography Identifies Clinical Classifiers of COVID-19

The COVID-19 pandemic has caused unparalleled challenges worldwide due to the variability in symptoms and rapid transmission. As the virus continues to surge across the U.S., there is an increasing de …

read more

27th Nov 2024

Successful Strategies for the Analysis of EtG and EtS in Urine

A report from the National Highway Traffic Administration reveals that alcohol-impaired drivers are responsible for nearly one-third of all traffic-related fatalities. Impaired driving can lead t …

read more

9th Apr 2024

How to Choose the Best Storage Vials

Solving Storage Challenges with F217 Liners Screw thread vials are common for LC sample analysis as well as sample or standard storage. But is there a difference between autosampler vials and stor …

read more

27th Mar 2024

Are Your Autosampler Vials Compromising Your Results?

Exploring the Impact of Vial Quality on HPLC and GC Performance In the world of chromatography, choosing the appropriate instrumentation and accessories is essential for achieving accurate and rel …

read more

4th Jan 2024

Revolutionizing Your Chromatography | The Power of Poroshell and more

Are you frustrated with increasing backpressures from your current HPLC column? Do you wish you could achieve UHPLC results with HPLC instrumentation? Choosing the proper tools for success is importan …

read more

8th May 2023

HPLC Pump Care and Troubleshooting

Many of the technical support inquiries we receive at Chrom Tech are related to care and troubleshooting of our continuous process pumps. Some of the topics include:    &nb …

read more

13th Feb 2023

How to Choose the Right Septa for Your Autosampler Vial Closure

When performing LC and GC analysis, you’ll need something to store and transport your samples prior to injection. Chromatography vials are the most common vessel, but come in a variety of shapes and s …

read more

18th Oct 2022

New and Dangerous Synthetic Opioids

Are New Synthetic Opioids Posing Increased Risks?Synthetic opioids are commonly used in clinical settings as they provide analgesic effects for individuals suffering from severe pain. Unfortunately, t …

read more

11th Oct 2022

Methods for Changing Peak Resolution in HPLC

Improving the resolution of closely eluting sample components is a challenge that all chromatographers will face at one time or another. Several methods for changing peak resolution in HPLC include us …

read more

18th Sep 2022

What is the Smallest Sample Volume You Can Use in 96 Well Plates?

For high throughput laboratories, 96-well plates offer a number of advantages over chromatography vials such as cost savings and easy automation capabilities. Different well plate types serve differen …

read more

15th Sep 2022

What Sample Prep is Best for Vitamin D Analysis?

Low level testing of endogenous vitamin and hormone levels in biological samples is the driving force behind the need for more sensitive and specific analytical methods. One example is vitamin D analy …

read more

12th Jul 2022

How Does ICP-MS Work?

How Does an ICP-MS Work?Inductively coupled plasma mass spectrometry (ICP-MS) is a method used to determine which elements something is made of, as opposed to molecules and compounds that are measured …

read more

12th Apr 2022

What LC Column Should I Use for EtG and EtS Detection?

Ethyl glucuronide (EtG) and ethyl sulfate (EtS) biomarkers are formed by the liver after ethanol ingestion. They can be detected in urine approximately 2-80 hours after alcohol is consumed. Due to the …

read more

11th Feb 2022

Method Transfer between Poroshell and Zorbax HPLC Columns

One of the primary benefits to using superficially porous particle (SPP) HPLC columns, as opposed to totally porous particles is the results yield the efficiency of sub-2-µm, fully porous columns, wit …

read more

19th Jan 2022

True Crime and Chromatography

People have always been fascinated by mystery, and in recent years there has been a major rise in true crime series: podcasts, tv shows, and even books. The horrible, gruesome tragedies have become a …

read more

19th Jan 2022

Reduce Instrument Downtime with Sample Preparation

Reducing downtime in the laboratory saves time and money spent on getting the instrument back up and running. One easy way to reduce the downtime of your HPLC is to prolong the life of your HPLC colum …

read more

4th Aug 2020

Applications of Chromatography

Chromatography is a vital tool used in many industries to determine the composition of a mixture. Chromatography is widely known for its role in scientific research, although it holds importance in ot …

read more