Blog

9th Apr 2024

How to Choose the Best Storage Vials

Solving Storage Challenges with F217 Liners Screw thread vials are common for LC sample analysis as well as sample or standard storage. But is there a difference between autosampler vials and stor …

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27th Mar 2024

Are Your Autosampler Vials Compromising Your Results?

Exploring the Impact of Vial Quality on HPLC and GC Performance In the world of chromatography, choosing the appropriate instrumentation and accessories is essential for achieving accurate and rel …

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5th Jan 2024

Revolutionizing Your Chromatography | The Power of Poroshell and more

Are you frustrated with increasing backpressures from your current HPLC column? Do you wish you could achieve UHPLC results with HPLC instrumentation? Choosing the proper tools for success is importan …

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8th May 2023

HPLC Pump Care and Troubleshooting

Many of the technical support inquiries we receive at Chrom Tech are related to care and troubleshooting of our continuous process pumps. Some of the topics include:    &nb …

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13th Feb 2023

How to Choose the Right Septa for Your Autosampler Vial Closure

When performing LC and GC analysis, you’ll need something to store and transport your samples prior to injection. Chromatography vials are the most common vessel, but come in a variety of shapes and s …

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18th Oct 2022

New and Dangerous Synthetic Opioids

Are New Synthetic Opioids Posing Increased Risks?Synthetic opioids are commonly used in clinical settings as they provide analgesic effects for individuals suffering from severe pain. Unfortunately, t …

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11th Oct 2022

Methods for Changing Peak Resolution in HPLC

Improving the resolution of closely eluting sample components is a challenge that all chromatographers will face at one time or another. Several methods for changing peak resolution in HPLC include us …

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18th Sep 2022

What is the Smallest Sample Volume You Can Use in 96 Well Plates?

For high throughput laboratories, 96-well plates offer a number of advantages over chromatography vials such as cost savings and easy automation capabilities. Different well plate types serve differen …

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15th Sep 2022

What Sample Prep is Best for Vitamin D Analysis?

Low level testing of endogenous vitamin and hormone levels in biological samples is the driving force behind the need for more sensitive and specific analytical methods. One example is vitamin D analy …

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12th Jul 2022

How Does ICP-MS Work?

How Does an ICP-MS Work?Inductively coupled plasma mass spectrometry (ICP-MS) is a method used to determine which elements something is made of, as opposed to molecules and compounds that are measured …

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12th Apr 2022

What LC Column Should I Use for EtG and EtS Detection?

Ethyl glucuronide (EtG) and ethyl sulfate (EtS) biomarkers are formed by the liver after ethanol ingestion. They can be detected in urine approximately 2-80 hours after alcohol is consumed. Due to the …

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11th Feb 2022

Method Transfer between Poroshell and Zorbax HPLC Columns

One of the primary benefits to using superficially porous particle (SPP) HPLC columns, as opposed to totally porous particles is the results yield the efficiency of sub-2-µm, fully porous columns, wit …

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19th Jan 2022

True Crime and Chromatography

People have always been fascinated by mystery, and in recent years there has been a major rise in true crime series: podcasts, tv shows, and even books. The horrible, gruesome tragedies have become a …

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19th Jan 2022

Reduce Instrument Downtime with Sample Preparation

Reducing downtime in the laboratory saves time and money spent on getting the instrument back up and running. One easy way to reduce the downtime of your HPLC is to prolong the life of your HPLC colum …

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9th Dec 2021

How to Connect a Syringe to HPLC Tubing

The need to connect a syringe to your LC pump to pull mobile phase through for priming (among other applications) is fairly common. We’ve seen some creative ways that people in the laboratory have con …

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15th Nov 2021

ASK BETHANY | Should I Use a Guard Column

HPLC ColumnsOne of the most important components in an LC system is the column, which is where analytes are separated out from a mixture for qualitative and quantitative analysis. HPLC columns need to …

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10th Nov 2021

What are the Benefits of Glass Vials in the Laboratory?

Chromatography vials are small glass or plastic vessels used in the lab to store and transport samples until they can be analyzed by HPLC or GC. Chances are, if you’re reading this, you probably do so …

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13th Sep 2021

ASK BEN | 4 Simple Steps to Find the Right GC Liner

We get a number of questions on GC liners, specifically what liner they should be using for their application. Choosing the appropriate GC inlet liner is crucial to ensure your sample can be proper …

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7th Sep 2021

How to Properly Swage HPLC Fittings

The ability to change and properly connect fittings on an HPLC is an important skill to have if you’re a chromatographer. To do any HPLC work, you’ll inevitably need to change or tighten a connecti …

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2nd Sep 2020

Environmental Applications of Chromatography

One of the biggest concerns in our world today is the state of the environment. Every day, our planet faces new challenges contributing to climate change, deforestation, and ozone depletion. Although, …

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26th Aug 2020

How to Select Chromatography Vials

Many factors play a role in deciding which vial is best for your needs such as sample volatility, sample amount, and light sensitivity. Choosing the right vial is imperative to increasing ROI and oper …

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26th Aug 2020

Reverse-Phase Liquid Chromatography vs. Hydrophilic Interaction Liquid Chromatography

Liquid Chromatography can be achieved through many methods including reverse-phase and hydrophilic interaction liquid chromatography (HILIC). Liquid chromatography is a form of column chromatography t …

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4th Aug 2020

Applications of Chromatography

Chromatography is a vital tool used in many industries to determine the composition of a mixture. Chromatography is widely known for its role in scientific research, although it holds importance in ot …

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16th Jul 2020

Chromatography Identifies Clinical Classifiers of COVID-19

The COVID-19 pandemic has created unprecedented struggles across the world due to symptom variability and high spread rate. As COVID-19 continues to surge through the U.S., there is an increasing need …

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2nd Dec 2019

Successful Strategies for the Analysis of EtG and EtS in Urine

In a report by the National Highway Traffic Administration, it was found that an alcohol-impaired driver was involved in nearly one-third of all traffic crash fatalities. Impaired driving can res …

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