How to Save Money and Increase Accuracy on Sample Prep

Automation can significantly enhance laboratory productivity by increasing throughput and precision in sample preparation. However, not every lab has the workload or budget for full automation. For tasks too large for manual pipetting but too small for full robotic systems, the Hamilton Microlab 600 offers the perfect balance. This semi-automated liquid handling system streamlines workflows, improves reproducibility, and reduces sample prep time by up to 50%—while minimizing rework and costly re-sampling.

Benefits of the Microlab 600

Preparing samples manually can be repetitive and error-prone. The Microlab 600 simplifies dilution and dispensing tasks with programmable methods and user-friendly controls. Operators can store common methods as “favorites,” minimizing setup time and variation between users. This semi-automated process increases accuracy, reduces fatigue, and delivers consistent results every time.

Dual Syringe Diluter

The Microlab 600 Dual Syringe Diluter uses two high-precision syringes to perform reproducible dilutions independent of viscosity, vapor pressure, or temperature. The system automatically flushes the tubing between samples, minimizing carryover even in sensitive analyses. Capable of creating dilutions up to 1:50,000 in a single step, it offers unmatched flexibility for research and analytical workflows.

The diluter is available in both Basic and Advanced controller options, with optional disposable-tip hand probes for sensitive applications where cross-contamination must be avoided.

Microlab 600 Dispensers

Hamilton’s Microlab 600 Dispenser line uses positive-displacement syringes to accurately dispense volumes from 100 nL to 50 mL. These dispensers maintain accuracy regardless of viscosity, volatility, or density. Using intuitive “Wizards,” users can easily perform repetitive or varied-volume dispenses with a single button press. Choose from three dispenser configurations based on your workflow needs:

Single Syringe Dispenser

The most cost-effective model, featuring one syringe pump for medium-throughput applications. Precision stepper motors refill from a reservoir automatically, offering faster, more consistent dispensing than traditional serological or repeating pipettes.

Dual Syringe Dispenser

The dual syringe configuration doubles efficiency and offers enhanced versatility. Common applications include:

• Dispensing into two containers simultaneously to double throughput
• Combining syringes for higher volume or faster dispenses
• Creating binary mixtures using separate reagents
• Performing dilution and sample spiking in one automated cycle

Continuous Dispenser

Designed for time-critical and manufacturing applications, the continuous dispenser alternates between filling and dispensing syringes. This ensures constant output without interruption—ideal for semi-automated or production-line integration.

Syringes and Liquid Handling Accessories

Chrom Tech is an authorized distributor of Hamilton syringes for both manual and autosampler applications in LC and GC systems. We stock a wide range of Hamilton manual syringes to ensure fast delivery and minimal downtime. Our experts can help you select the correct syringe configuration for your instrument and analytical needs.

Conclusion

The Hamilton Microlab 600 bridges the gap between manual and fully automated liquid handling. With configurable diluters, dispensers, and syringe options, it offers unmatched flexibility and accuracy for modern analytical labs. By adopting semi-automation, laboratories can reduce variability, enhance reproducibility, and achieve greater efficiency in daily sample preparation.