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Posted by Chrom Tech on 15th Oct 2025

Fuel Ethanol Fermentation Analysis by HPLC

Optimizing Ethanol Fermentation Analysis with HPLC Ethanol production continues to grow worldwide as demand for renewable energy sources increases. Ethanol is typically produced by fermenting renewab …

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Posted by Chrom Tech on 15th Oct 2025

The Advantages of Silane-Treated Vials

The Advantages of Silane-Treated Vials In chromatography, even minor analyte loss can significantly affect quantitative accuracy—especially in trace-level analyses. Silane-treated vials help pr …

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Posted by Chrom Tech on 15th Oct 2025

The Different 96 Well Plate Bottom Shapes

Understanding 96-Well Plate Designs and Applications Chrom Tech’s 96-well plates are a cornerstone in high-throughput chromatography and mass spectrometry workflows, enabling automation from sa …

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Posted by Chrom Tech on 15th Oct 2025

A Sneak Peak into the Largest HPLC Industry in the World - Biotechnology Applications

HPLC in Biotechnology: Advancing Analytical Precision Biotechnology is one of the world’s largest and most rapidly evolving industries, spanning applications in food and agriculture, pharmaceut …

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Posted by Chrom Tech on 15th Oct 2025

New and Dangerous Synthetic Opioids

Are New Synthetic Opioids Increasing Risks? Synthetic opioids are critical tools in modern medicine for managing severe pain. However, their extreme potency and addictive potential make them dangerou …

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Posted by Chrom Tech on 15th Oct 2025

Inline Filters vs. Guard Columns for HPLC

Protecting Your HPLC Columns: The Role of Filters and Guard Columns In high-performance liquid chromatography (HPLC), filters such as inline filters, pre-column filters, and guard columns play an ess …

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Posted by Chrom Tech on 14th Oct 2025

The Different Types of Well Plates: Polypropylene and 96 Well Plates With Glass Inserts

What Are the Dimensions of a 96 Deep Well Plate? Chrom Tech 96 well microplates are designed according to ANSI/SLAS footprint standards, ensuring compatibility with all leading microplate readers, li …

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Posted by Chrom Tech on 14th Oct 2025

How To Choose the Right Headspace Vial Cap

Why Choose Headspace GC? Headspace gas chromatography (GC) is a widely used analytical method for detecting volatile organic compounds (VOCs) such as alcohols, solvents, residual monomers, and flavor …

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Posted by Chrom Tech on 14th Oct 2025

Helpful Fluoropolymer Tubing Guide for Your HPLC Applications

What Types of Tubing Are Used in the Laboratory? In liquid chromatography and general laboratory fluidic systems, a wide range of tubing materials and configurations are available to meet specific ne …

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Posted by Chrom Tech on 14th Oct 2025

How Do You Dispose of HPLC Waste?

High-Performance Liquid Chromatography (HPLC) is an essential analytical technique used across industries to separate complex mixtures into individual components. Whether quantifying unknown analytes …

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Posted by Chrom Tech on 14th Oct 2025

Detecting Synthetic Opioids With an Agilent HPLC and Poroshell Column

The opioid epidemic continues to pose a serious challenge for the medical and forensic communities. Since 1999, unintentional overdose deaths involving opioid pain relievers have more than quadruple …

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Posted by Chrom Tech on 14th Oct 2025

ASK BEN | How to Choose an HPLC or GC Syringe

Syringes play a vital role in both HPLC and GC systems. For accurate analysis on a liquid or gas chromatography column, samples must be precisely introduced into the flow path—this is the syri …

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Posted by Chrom Tech on 14th Oct 2025

How to Properly Swage HPLC Fittings

Learning how to properly install and tighten HPLC fittings is a key skill for every chromatographer. Whether you’re setting up a new system or performing routine maintenance, you’ll event …

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Posted by Chrom Tech on 14th Oct 2025

4 Questions You Should Ask Before Buying an HPLC Pump

Chrom Tech’s positive-displacement piston pumps are engineered for precision and versatility, serving a wide range of analytical, clinical, preparative, and fluid-metering applications. While m …

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Posted by Chrom Tech on 14th Oct 2025

Extra HPLC Pump Parts You Need To Have on Hand

Modern HPLC pumps are designed for long-term, reliable performance — often running 24 hours a day, 7 days a week, 365 days a year. To keep your system operating at peak efficiency, it’s e …

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Posted by Chrom Tech on 14th Oct 2025

An Essential Guide to HPLC Fittings for Your Laboratory

An Introduction to HPLC Fittings HPLC fittings play a vital role in chromatography systems, connecting tubing, adapters, and components to ensure leak-free, stable operation. Secure connections are c …

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Posted by Chrom Tech on 14th Oct 2025

ASK BEN | 4 Simple Steps to Find the Right GC Liner

Choosing the right GC inlet liner is essential for achieving accurate and reproducible gas chromatography results. The liner ensures that the correct amount of sample is transferred to the GC column …

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Posted by Chrom Tech on 14th Oct 2025

How to Connect a Syringe to HPLC Tubing

In chromatography and LC applications, connecting a syringe to your pump for priming or maintenance is a common and essential task. Many labs have improvised solutions for this connection, but Chrom …

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Posted by Chrom Tech on 14th Oct 2025

Reduce Instrument Downtime with Sample Preparation

Reducing downtime in your chromatography lab not only maximizes productivity but also minimizes the costs of maintenance and instrument repair. One of the most effective ways to achieve this is by ex …

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Posted by Chrom Tech on 14th Oct 2025

True Crime and Chromatography

True crime has long captivated audiences, blending real-life mystery, suspense, and forensic science into compelling storytelling. Whether through podcasts, documentaries, or books, these stories inv …

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Posted by Chrom Tech on 14th Oct 2025

Method Transfer between Poroshell and Zorbax HPLC Columns

Superficially porous particle (SPP) HPLC columns offer one of the most effective ways to achieve high chromatographic efficiency without the excessive backpressure typically associated with sub-2-&mu …

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Posted by Chrom Tech on 14th Oct 2025

How do Stainless-Steel Fittings Differ from Polymer-Based Fittings?

Both stainless-steel and polymer-based fittings are widely used in HPLC systems, each offering distinct advantages depending on the laboratory’s pressure requirements, sample type, and analytic …

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Posted by Chrom Tech on 14th Oct 2025

Using 96 Well Plates In High Throughput Laboratories

For high-throughput laboratories, switching from traditional autosampler vials to 96-well plates offers substantial advantages—particularly in automation, consistency, and time savings. While n …

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Posted by Chrom Tech on 14th Oct 2025

What LC Column Should I Use for EtG and EtS Detection?

Ethyl glucuronide (EtG) and ethyl sulfate (EtS) are direct metabolites of ethanol produced in the liver after alcohol consumption. These highly polar compounds are excellent biomarkers for recent alc …

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Posted by Chrom Tech on 14th Oct 2025

Revisiting ‘The Big Pain’

During the pandemic, drug testing laboratories faced unprecedented strain as resources shifted toward COVID-19 testing. This caused other forms of testing—such as routine employee drug screenin …

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Posted by Chrom Tech on 14th Oct 2025

One Simple Step to Conserve Helium

The ongoing helium shortage continues to impact gas chromatography (GC) laboratories worldwide. While alternative carrier gases such as hydrogen or nitrogen can sometimes replace helium, we understan …

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Posted by Chrom Tech on 14th Oct 2025

Safety Waste Compliance in One Easy Step

Improper waste collection and handling of hazardous materials can pose serious health and safety risks in any laboratory. While the days of disposing HPLC solvent waste down the drain are long gone, …

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Posted by Chrom Tech on 14th Oct 2025

How Does ICP-MS Work?

Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is a powerful analytical technique used to identify and quantify elements within a sample. Unlike LC/MS and GC/MS—which target molecules an …

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Posted by Chrom Tech on 14th Oct 2025

What Sample Prep is Best for Vitamin D Analysis?

With growing demand for sensitive and specific analytical techniques, laboratories are increasingly focusing on accurate low-level detection of endogenous vitamins and hormones in biological samples. …

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Posted by Chrom Tech on 14th Oct 2025

What is the Smallest Sample Volume You Can Use in 96 Well Plates?

For high-throughput laboratories, 96-well plates have become a cornerstone of efficient sample handling. Compared to chromatography vials, they offer significant benefits in cost savings, automation …

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Posted by Chrom Tech on 14th Oct 2025

Should You Use a Glass Pre-Filter Syringe Filter?

Proper sample filtration is a key step in chromatography that directly impacts both analytical accuracy and instrument performance. High-quality filtration ensures consistent, reliable results while …

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Posted by Chrom Tech on 14th Oct 2025

Why You Should be Using a Delay Column for PFAS Analysis

PFAS in the Environment Today Poly- and perfluoroalkyl substances (PFAS)—commonly referred to as “forever chemicals”—have become a growing global concern due to their persiste …

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Posted by Chrom Tech on 14th Oct 2025

Methods for Changing Peak Resolution in HPLC

Achieving clear separation between closely eluting peaks is one of the most common challenges faced by chromatographers. Optimizing peak resolution in HPLC involves fine-tuning three key factors: re …

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Posted by Chrom Tech on 14th Oct 2025

How to Check for Leaks in a GC System

Maintaining a leak-free GC or GC/MS system is essential for producing reliable, reproducible, and accurate chromatographic results. Even minor gas leaks can compromise sensitivity, contaminate sample …

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Posted by Chrom Tech on 14th Oct 2025

What Should Forensic Labs Be Using for Blood Alcohol Testing?

Headspace GC-FID (Gas Chromatography with Flame Ionization Detection) using dual columns is the industry standard for accurately measuring blood alcohol concentration (BAC) in forensic laboratories. …

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Posted by Chrom Tech on 14th Oct 2025

Maximizing Throughput in an HPLC Laboratory

Increasing sample throughput is one of the most effective ways for laboratories to boost productivity and reduce operating costs. While optimizing HPLC analysis efficiency is crucial, cost savings ca …

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Posted by Chrom Tech on 14th Oct 2025

Syringe Filters vs Filter Vials: What is the Best Method for Filtration?

In chromatography, most samples taken directly from their source require some level of sample preparation before injection into the analytical instrument. The goal is to remove particulates and conta …

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Posted by Chrom Tech on 14th Oct 2025

The 3 Most Common Applications for Headspace Vials

Gas chromatography (GC) is an essential analytical technique used to separate and analyze volatile substances in complex mixtures. A specialized method known as headspace gas chromatography (HS-GC) f …

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Posted by Chrom Tech on 14th Oct 2025

EHS Compliance: Safely Manage HPLC Solvent Waste

Many solvents and samples used in high-performance liquid chromatography (HPLC) are flammable or hazardous. To protect your lab and personnel, proper HPLC solvent waste disposal is critical. Chrom Te …

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Posted by Chrom Tech on 14th Oct 2025

Revolutionizing UHPLC Connections: Introducing MarvelXACT by IDEX

Reliable HPLC fittings are essential for achieving accurate and consistent results in UHPLC (Ultra-High Performance Liquid Chromatography). Improper fittings can lead to leaks, inconsistent data, and …

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Posted by Chrom Tech on 14th Oct 2025

Measuring Gas Flow for Gas Chromatography

Maximizing Efficiency with the Agilent ADM Flow MeterDiscover how the Agilent ADM Flow Meter enhances laboratory efficiency through accurate, real-time dry gas flow measurement for gas chromatograph …

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Posted by Chrom Tech on 14th Oct 2025

How Many Injections Can I Get on My HPLC Column?

It depends! Several factors influence how many injections you can perform on your HPLC column, including: Injecting “dirty” samples Following the operating conditions recommended by the …

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Posted by Chrom Tech on 14th Oct 2025

How To Maximize HPLC Column Lifetime

All HPLC columns experience gradual wear over time. Factors such as sample injections, residual proteins, lipids, and particulates can accumulate inside the column, leading to increased backpressure …

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Posted by Chrom Tech on 14th Oct 2025

How to Save Money and Increase Accuracy on Sample Prep

Automation can significantly enhance laboratory productivity by increasing throughput and precision in sample preparation. However, not every lab has the workload or budget for full automation. For t …

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Posted by Chrom Tech on 14th Oct 2025

The Role of Solvent Gradients in HPLC Analysis and How ASI Static Mixers Can Improve Performance

High-Performance Liquid Chromatography (HPLC) is a cornerstone technique in analytical chemistry, used to separate, identify, and quantify components in complex mixtures. One of the most influential …

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Posted by Chrom Tech on 14th Oct 2025

Should I Use a Guard Column

In any liquid chromatography (LC) system, the HPLC column is the heart of the separation process. It is here that analytes are isolated for both qualitative and quantitative analysis. While HPLC colu …

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Posted by Chrom Tech on 14th Oct 2025

The Benefits of Glass Well Plate Inserts

96-well plates are essential consumables in high-throughput analytical laboratories, particularly those using mass spectrometry workflows. The most common formats—polypropylene 96 deep-well pl …

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Posted by Chrom Tech on 14th Oct 2025

Are Hydrogen Generators Safe?

Laboratories traditionally rely on compressed hydrogen cylinders for their gas supply, but this approach carries safety concerns and can cause unexpected downtime when deliveries are delayed. Switch …

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