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Posted by Chrom Tech on 15th Oct 2025

What is ICP-MS Used For?

The Inductively Coupled Plasma–Mass Spectrometer (ICP-MS) is one of the most powerful and sensitive analytical instruments available for elemental analysis. Commonly known simply as ICP-MS, it …

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Posted by Chrom Tech on 15th Oct 2025

Which Pumps Are Used in HPLC?

High-performance liquid chromatography (HPLC) relies on precision pumping systems to deliver solvents at a consistent, controlled flow rate and pressure. The right pump type ensures accurate separati …

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Posted by Chrom Tech on 15th Oct 2025

Using Hydrogen as a Carrier Gas for Gas Chromatography

Hydrogen as a Carrier Gas Hydrogen is quickly becoming a preferred carrier gas for gas chromatography (GC) due to its efficiency, cost-effectiveness, and renewable availability. As helium supplies be …

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Posted by Chrom Tech on 15th Oct 2025

Environmental Applications of Chromatography

As global awareness of environmental challenges continues to rise, the need for advanced analytical tools has never been greater. Climate change, deforestation, and chemical pollution all threaten th …

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Posted by Chrom Tech on 15th Oct 2025

The Difference Between Superficially Porous and Fully Porous Particles

In liquid chromatography, the particle design of an HPLC column directly affects resolution, efficiency, and pressure. The two most common types—superficially porous particles (SPPs) and fully …

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Posted by Chrom Tech on 15th Oct 2025

Understanding How mRNA Vaccines Are Produced

Messenger RNA (mRNA) vaccines represent one of the most significant advancements in modern medicine. These vaccines use lipid nanoparticles (LNPs) to safely deliver genetic instructions that teach th …

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Posted by Chrom Tech on 15th Oct 2025

PEEK Tubing: What It Is and the Different Types

Polyetheretherketone (PEEK) tubing is a high-performance polymer widely used in chromatography applications. Known for its mechanical strength, flexibility, and resistance to harsh solvents, PEEK has …

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Posted by Chrom Tech on 15th Oct 2025

Tips for How to Prime an HPLC Pump

Properly priming your HPLC pump is one of the simplest yet most essential steps in maintaining reliable system performance. Whether you’re setting up a new system, switching solvents, or restar …

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Posted by Chrom Tech on 15th Oct 2025

3 Ways to Reduce Long Lead Times

Over the past few years, laboratories have grown all too familiar with the phrase “supply chain issues.” Extended lead times can disrupt workflows, delay projects, and strain budgets. For …

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Posted by Chrom Tech on 15th Oct 2025

Cost Savings on Autosampler Vials for Chromatography

As research laboratories navigate tightening budgets, managers are increasingly challenged to reduce costs without compromising analytical precision or productivity. Chrom Tech supports this balance …

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Posted by Chrom Tech on 15th Oct 2025

How To Make an HPLC Connection With PEEK Tubing

Making an HPLC Connection With PEEK Tubing Creating a proper HPLC connection is essential for ensuring leak-free performance and consistent chromatographic results. With PEEK (Polyetheretherketone) t …

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Posted by Chrom Tech on 15th Oct 2025

What Column Should I Use for Carbohydrate Analysis?

Why Carbohydrate Analysis Matters In food science and analytical chemistry, carbohydrate analysis plays a vital role in ensuring the quality, taste, and consistency of food products. High-Performance …

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Posted by Chrom Tech on 15th Oct 2025

Fuel Ethanol Fermentation Analysis by HPLC

Optimizing Ethanol Fermentation Analysis with HPLC Ethanol production continues to grow worldwide as demand for renewable energy sources increases. Ethanol is typically produced by fermenting renewab …

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Posted by Chrom Tech on 15th Oct 2025

The Advantages of Silane-Treated Vials

The Advantages of Silane-Treated Vials In chromatography, even minor analyte loss can significantly affect quantitative accuracy—especially in trace-level analyses. Silane-treated vials help pr …

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Posted by Chrom Tech on 15th Oct 2025

A Sneak Peak into the Largest HPLC Industry in the World - Biotechnology Applications

HPLC in Biotechnology: Advancing Analytical Precision Biotechnology is one of the world’s largest and most rapidly evolving industries, spanning applications in food and agriculture, pharmaceut …

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Posted by Chrom Tech on 15th Oct 2025

New and Dangerous Synthetic Opioids

Are New Synthetic Opioids Increasing Risks? Synthetic opioids are critical tools in modern medicine for managing severe pain. However, their extreme potency and addictive potential make them dangerou …

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Posted by Chrom Tech on 15th Oct 2025

Inline Filters vs. Guard Columns for HPLC

Protecting Your HPLC Columns: The Role of Filters and Guard Columns In high-performance liquid chromatography (HPLC), filters such as inline filters, pre-column filters, and guard columns play an ess …

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Posted by Chrom Tech on 14th Oct 2025

How To Choose the Right Headspace Vial Cap

Why Choose Headspace GC? Headspace gas chromatography (GC) is a widely used analytical method for detecting volatile organic compounds (VOCs) such as alcohols, solvents, residual monomers, and flavor …

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Posted by Chrom Tech on 14th Oct 2025

Helpful Fluoropolymer Tubing Guide for Your HPLC Applications

What Types of Tubing Are Used in the Laboratory? In liquid chromatography and general laboratory fluidic systems, a wide range of tubing materials and configurations are available to meet specific ne …

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Posted by Chrom Tech on 14th Oct 2025

Detecting Synthetic Opioids With an Agilent HPLC and Poroshell Column

The opioid epidemic continues to pose a serious challenge for the medical and forensic communities. Since 1999, unintentional overdose deaths involving opioid pain relievers have more than quadruple …

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Posted by Chrom Tech on 14th Oct 2025

How to Properly Swage HPLC Fittings

Learning how to properly install and tighten HPLC fittings is a key skill for every chromatographer. Whether you’re setting up a new system or performing routine maintenance, you’ll event …

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Posted by Chrom Tech on 14th Oct 2025

4 Questions You Should Ask Before Buying an HPLC Pump

Chrom Tech’s positive-displacement piston pumps are engineered for precision and versatility, serving a wide range of analytical, clinical, preparative, and fluid-metering applications. While m …

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Posted by Chrom Tech on 14th Oct 2025

Extra HPLC Pump Parts You Need To Have on Hand

Modern HPLC pumps are designed for long-term, reliable performance — often running 24 hours a day, 7 days a week, 365 days a year. To keep your system operating at peak efficiency, it’s e …

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Posted by Chrom Tech on 14th Oct 2025

An Essential Guide to HPLC Fittings for Your Laboratory

An Introduction to HPLC Fittings HPLC fittings play a vital role in chromatography systems, connecting tubing, adapters, and components to ensure leak-free, stable operation. Secure connections are c …

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Posted by Chrom Tech on 14th Oct 2025

ASK BEN | 4 Simple Steps to Find the Right GC Liner

Choosing the right GC inlet liner is essential for achieving accurate and reproducible gas chromatography results. The liner ensures that the correct amount of sample is transferred to the GC column …

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Posted by Chrom Tech on 14th Oct 2025

How to Connect a Syringe to HPLC Tubing

In chromatography and LC applications, connecting a syringe to your pump for priming or maintenance is a common and essential task. Many labs have improvised solutions for this connection, but Chrom …

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Posted by Chrom Tech on 14th Oct 2025

Reduce Instrument Downtime with Sample Preparation

Reducing downtime in your chromatography lab not only maximizes productivity but also minimizes the costs of maintenance and instrument repair. One of the most effective ways to achieve this is by ex …

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Posted by Chrom Tech on 14th Oct 2025

True Crime and Chromatography

True crime has long captivated audiences, blending real-life mystery, suspense, and forensic science into compelling storytelling. Whether through podcasts, documentaries, or books, these stories inv …

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Posted by Chrom Tech on 14th Oct 2025

Method Transfer between Poroshell and Zorbax HPLC Columns

Superficially porous particle (SPP) HPLC columns offer one of the most effective ways to achieve high chromatographic efficiency without the excessive backpressure typically associated with sub-2-&mu …

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Posted by Chrom Tech on 14th Oct 2025

How do Stainless-Steel Fittings Differ from Polymer-Based Fittings?

Both stainless-steel and polymer-based fittings are widely used in HPLC systems, each offering distinct advantages depending on the laboratory’s pressure requirements, sample type, and analytic …

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Posted by Chrom Tech on 14th Oct 2025

What LC Column Should I Use for EtG and EtS Detection?

Ethyl glucuronide (EtG) and ethyl sulfate (EtS) are direct metabolites of ethanol produced in the liver after alcohol consumption. These highly polar compounds are excellent biomarkers for recent alc …

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Posted by Chrom Tech on 14th Oct 2025

Revisiting ‘The Big Pain’

During the pandemic, drug testing laboratories faced unprecedented strain as resources shifted toward COVID-19 testing. This caused other forms of testing—such as routine employee drug screenin …

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Posted by Chrom Tech on 14th Oct 2025

One Simple Step to Conserve Helium

The ongoing helium shortage continues to impact gas chromatography (GC) laboratories worldwide. While alternative carrier gases such as hydrogen or nitrogen can sometimes replace helium, we understan …

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Posted by Chrom Tech on 14th Oct 2025

How Does ICP-MS Work?

Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is a powerful analytical technique used to identify and quantify elements within a sample. Unlike LC/MS and GC/MS—which target molecules an …

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Posted by Chrom Tech on 14th Oct 2025

What Sample Prep is Best for Vitamin D Analysis?

With growing demand for sensitive and specific analytical techniques, laboratories are increasingly focusing on accurate low-level detection of endogenous vitamins and hormones in biological samples. …

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Posted by Chrom Tech on 14th Oct 2025

Should You Use a Glass Pre-Filter Syringe Filter?

Proper sample filtration is a key step in chromatography that directly impacts both analytical accuracy and instrument performance. High-quality filtration ensures consistent, reliable results while …

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Posted by Chrom Tech on 14th Oct 2025

Why You Should be Using a Delay Column for PFAS Analysis

PFAS in the Environment Today Poly- and perfluoroalkyl substances (PFAS)—commonly referred to as “forever chemicals”—have become a growing global concern due to their persiste …

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Posted by Chrom Tech on 14th Oct 2025

Methods for Changing Peak Resolution in HPLC

Achieving clear separation between closely eluting peaks is one of the most common challenges faced by chromatographers. Optimizing peak resolution in HPLC involves fine-tuning three key factors: re …

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Posted by Chrom Tech on 14th Oct 2025

How to Check for Leaks in a GC System

Maintaining a leak-free GC or GC/MS system is essential for producing reliable, reproducible, and accurate chromatographic results. Even minor gas leaks can compromise sensitivity, contaminate sample …

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Posted by Chrom Tech on 14th Oct 2025

What Should Forensic Labs Be Using for Blood Alcohol Testing?

Headspace GC-FID (Gas Chromatography with Flame Ionization Detection) using dual columns is the industry standard for accurately measuring blood alcohol concentration (BAC) in forensic laboratories. …

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Posted by Chrom Tech on 14th Oct 2025

Maximizing Throughput in an HPLC Laboratory

Increasing sample throughput is one of the most effective ways for laboratories to boost productivity and reduce operating costs. While optimizing HPLC analysis efficiency is crucial, cost savings ca …

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Posted by Chrom Tech on 14th Oct 2025

Syringe Filters vs Filter Vials: What is the Best Method for Filtration?

In chromatography, most samples taken directly from their source require some level of sample preparation before injection into the analytical instrument. The goal is to remove particulates and conta …

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Posted by Chrom Tech on 14th Oct 2025

The 3 Most Common Applications for Headspace Vials

Gas chromatography (GC) is an essential analytical technique used to separate and analyze volatile substances in complex mixtures. A specialized method known as headspace gas chromatography (HS-GC) f …

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Posted by Chrom Tech on 14th Oct 2025

Revolutionizing UHPLC Connections: Introducing MarvelXACT by IDEX

Reliable HPLC fittings are essential for achieving accurate and consistent results in UHPLC (Ultra-High Performance Liquid Chromatography). Improper fittings can lead to leaks, inconsistent data, and …

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Posted by Chrom Tech on 14th Oct 2025

How Many Injections Can I Get on My HPLC Column?

It depends! Several factors influence how many injections you can perform on your HPLC column, including: Injecting “dirty” samples Following the operating conditions recommended by the …

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Posted by Chrom Tech on 14th Oct 2025

How To Maximize HPLC Column Lifetime

All HPLC columns experience gradual wear over time. Factors such as sample injections, residual proteins, lipids, and particulates can accumulate inside the column, leading to increased backpressure …

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Posted by Chrom Tech on 14th Oct 2025

How to Save Money and Increase Accuracy on Sample Prep

Automation can significantly enhance laboratory productivity by increasing throughput and precision in sample preparation. However, not every lab has the workload or budget for full automation. For t …

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Posted by Chrom Tech on 14th Oct 2025

The Role of Solvent Gradients in HPLC Analysis and How ASI Static Mixers Can Improve Performance

High-Performance Liquid Chromatography (HPLC) is a cornerstone technique in analytical chemistry, used to separate, identify, and quantify components in complex mixtures. One of the most influential …

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