Chromatography Vials

Vial Selection, Compatibility, and Quality You Can Trust

Chrom Tech offers a complete range of chromatography vials, inserts, and closures featuring 1.5 mL, 2 mL, Clear and Amber Vials, Inserts, and Caps - Compatible with Agilent, Shimadzu, Thermo, Waters Instruments. Available in glass or plastic, these vials ensure leak-free performance, accurate sample recovery, and secure sealing for reliable results.

Choosing the right vial depends on sample volatility, sensitivity, and system compatibility. The industry standard 12 × 32 mm vial fits most autosamplers, while 20 mm headspace vials are used for specialized gas analysis. Screw thread, crimp, and snap top formats allow flexible closure options for every workflow.

Screw thread vials are the preferred HPLC vial due to easy handling and tool-free caps. Crimp vials are the ideal GC vial, minimizing evaporation and ensuring tamper resistance. Snap top vials offer fast, convenient sealing for high-throughput environments.

Vials are available in Type I borosilicate glass for inertness, or in polypropylene and TPX polymer for cost-effective and chemical-resistant use. Use amber or black vials for light-sensitive samples, and pair them with PTFE/F217 closures for secure, resealable storage.

For limited sample volumes, Chrom Tech supplies pre-loaded vial inserts and low-volume configurations to minimize waste and maximize precision. Common vials and closures are stocked and ready to ship for immediate lab use. for expert help selecting the right vial system for your application.


Vial Categories

Explore popular chromatography vials from Chrom Tech


Chromatography Vial Glossary â–¸
Autosampler Vial
A precision-manufactured vial used in automation systems to deliver samples into HPLC, UHPLC, or GC instruments.
Crimp-Top Vial
A chromatography vial sealed using an aluminum crimp cap for maximum sealing strength—ideal for GC applications.
Screw-Top Vial
A vial with a threaded neck that accepts screw caps, widely used in HPLC and LC/MS workflows.
Snap-Top Vial
A convenience-focused vial with a snap-fit closure, enabling quick sealing without tools.
Headspace Vial
A thick-walled vial designed for heated headspace GC analysis, allowing pressure build-up during sample equilibration.
Vial Insert
A small inner sleeve used to enable low-volume injections or ensure the autosampler needle reaches the sample.
Septum (Septa)
A pierceable silicone/PTFE sealing layer inside vial caps, ensuring sample containment without contamination.
Amber Glass
UV-blocking borosilicate glass used to protect light-sensitive compounds from photodegradation.
Polypropylene (PP)
A chemically resistant polymer used when glass is unsuitable—ideal for trace-metal or bioanalytical workflows.
Chromatography Vial Categories â–¸
Threaded chromatography vials widely used for HPLC and LC/MS workflows.
Tight-sealing vials ideal for GC and elevated temperature workflows.
Convenient snap-fit closure vials for autosamplers requiring fast turnaround.
Thick-walled vials engineered for heated headspace GC equilibration.
Inner sleeves enabling low-volume injections or improved needle reach.
Closures incorporating pierceable septa to maintain sample integrity.
Frequently Asked Questions â–¸

Which vial type should I use for GC vs. HPLC applications?

Crimp vials are recommended for GC due to superior sealing and evaporation control, while screw or snap top vials are preferred for HPLC and LCMS systems.

What vial material is best for light-sensitive samples?

Amber glass or black polypropylene vials block UV and visible light, protecting light-sensitive analytes from degradation during handling and storage.

Do Chrom Tech vials fit all autosamplers?

Yes. Chrom Tech vials conform to standard autosampler dimensions and are compatible with Agilent, Thermo Fisher, Shimadzu, Waters, and other major LC/GC instruments.