Agilent J&W Specialty Columns

DB-HeavyWAX is a high-capacity WAX (PEG-type) specialty column designed for challenging oxygenated mixtures where standard WAX phases may overload or lose resolution. It is commonly selected for heavier alcohols, glycols, and complex solvent/oxygenate profiles.

• You need WAX/PEG selectivity but higher capacity for heavier oxygenates
• Samples contain complex matrices that challenge standard WAX columns
• You want improved separation of higher-boiling oxygenated compounds

DB-WAX and DB-WAXFF are WAX (PEG) specialty columns widely used for oxygenates, flavor compounds, and solvent mixtures where strong polar selectivity improves resolution. They are a common choice for alcohols, aldehydes, ketones, esters, and related oxygenated analytes.

• Oxygenated VOCs and solvent profiling
• Flavor & fragrance separations
• Polar analytes that do not resolve well on DB-5 / DB-1 type phases

DB-WAXetr is a specialty WAX phase optimized for improved inertness and trace-level performance. It is commonly selected when polar oxygenates show adsorption, tailing, or low recovery on standard WAX columns.

• Trace-level oxygenates and polar volatiles
• Improved peak shape is needed for active polar compounds
• You want WAX selectivity with better recovery and reproducibility

HP-INNOWAX is a widely used polar WAX (PEG) column in the HP series, selected for oxygenates, flavors, and polar VOC profiles where strong polarity-driven retention improves separation.

• Routine oxygenate and solvent separations
• Flavor & fragrance workflows
• Polar VOCs that coelute on low-polarity phases

CP-WAX 52 CB is a polar WAX specialty column used for oxygenates and solvent mixtures requiring strong polarity-driven selectivity. It is often chosen to improve resolution of polar volatiles and reduce coelution in complex oxygenate profiles.

• Oxygenated VOC profiles and solvent separations
• Improving resolution vs DB-5/DB-1 type phases
• Polar compounds requiring strong retention

Carbowax 20M / HP-20M is a classic PEG WAX chemistry used for polar volatiles and oxygenates. It is commonly selected for solvent panels, flavor compounds, and general polar GC applications where PEG selectivity improves resolution.

• Polar VOC and oxygenate screening
• Flavor and fragrance separations
• Solvent profiling with strong polarity selectivity

HP-FFAP is an FFAP-type specialty phase designed for strong retention and improved peak shape of free fatty acids and organic acids. It is commonly used for fatty acid profiling and acidic volatile separations where standard WAX phases may show tailing or poor recovery.

• Free fatty acids and short-chain organic acids
• Improved peak shape for acidic analytes
• Food, fermentation, and biodiesel-related profiling

DB-FFAP provides FFAP selectivity for acidic analytes, supporting strong retention and improved peak shapes for free fatty acids and organic acids. It is frequently selected for method development where acid analyte recovery and symmetry are critical.

• Organic acid profiling and free fatty acids
• Acid-sensitive compounds needing improved recovery
• Food and fermentation volatile acid analysis

High Temperature specialty columns are engineered for elevated oven programs needed to elute higher-boiling compounds and heavy matrices. They are selected when standard columns cannot tolerate the thermal conditions required for late-eluting analytes.

• High-boiling SVOCs and heavy hydrocarbon fractions
• Methods requiring elevated final oven temperatures
• Reducing late-run bleed and improving baseline stability

Petroleum specialty columns are designed for hydrocarbon and petrochemical workflows where volatility-driven separation, carbon-number distribution, and robust performance are priorities. They are commonly used for refinery, fuels, and industrial hydrocarbon profiling.

• Hydrocarbon profiling and carbon number distribution
• Fuel, refinery, and petrochemical QC methods
• Robust separations for complex hydrocarbon matrices

Select Biodiesel columns are engineered for biodiesel characterization and FAME-related workflows. They are selected to improve resolution of complex ester mixtures, support compliance-style methods, and sharpen separations where conventional phases struggle with overlapping ester profiles.

• Biodiesel and FAME profile separations
• Improving ester resolution and quantitation reliability
• Method-driven fuel testing workflows

Amines specialty columns are designed to improve peak shape and recovery for basic compounds that commonly interact with active sites. They are chosen to reduce tailing, stabilize retention, and improve quantitation of amines in complex matrices.

• Primary/secondary/tertiary amines with tailing issues
• Improved recovery for basic analytes at trace levels
• More reliable quantitation and peak symmetry

Pesticides specialty columns are built to support common pesticide screening and confirmatory methods, prioritizing selectivity control, low bleed (for MS), and reliable recoveries for challenging analytes.

• Multi-residue pesticide screening and confirmation
• GC/MS workflows requiring stable baselines (low bleed)
• Improved separation of structurally similar pesticide compounds

PAH specialty columns are optimized for polycyclic aromatic hydrocarbon separation where aromatic selectivity, isomer resolution, and stable retention are critical. They are commonly used for environmental and industrial PAH monitoring workflows.

• PAH panels requiring improved isomer resolution
• Environmental monitoring and industrial compliance workflows
• Complex aromatic mixtures that coelute on general-purpose phases

Semivolatile specialty columns are designed to deliver broad SVOC coverage with stable retention, good peak shape, and low background signal for MS workflows. They are selected for environmental and industrial SVOC panels where late-eluters and complex matrices are common.

• EPA-style SVOC panels and broad screening
• Complex samples with many late-eluting compounds
• Improved robustness and baseline stability for GC/MS

Volatile specialty columns are optimized for volatile organic compound separations where fast analysis, stable retention, and reliable early peak separation are critical. They are commonly used for residual solvent methods and VOC screening workflows.

• VOC panels and residual solvent screening
• Fast cycle time methods with early eluters
• Improved volatility-based separation control

Flavors & Fragrances specialty columns are selected to resolve complex aroma mixtures, including oxygenates, esters, terpenes, and related volatile components. They emphasize selectivity and peak shape in samples with many closely eluting compounds.

• Flavor, fragrance, and essential oil profiling
• Complex oxygenate and terpene mixtures
• Improved resolution of closely related aroma compounds

Life Sciences specialty columns support bioanalytical and life science workflows where complex matrices, trace targets, and reliable recoveries matter. They are selected to improve method robustness and to help manage adsorption or matrix-driven peak issues.

• Bioanalytical screening and confirmatory GC methods
• Trace targets in complex biological or pharmaceutical matrices
• Improved recovery and peak shape for active compounds

Metal Columns emphasize rugged handling and durability in environments where traditional fused silica may be difficult to manage. They are selected for applications that benefit from improved robustness during installation, transport, or repeated column changes.

• Rugged labs needing improved handling durability
• High-throughput environments with frequent column changes
• Situations where fused silica breakage risk is a concern

PLOT Columns (porous layer open tubular) are engineered for permanent gases and very light hydrocarbons where conventional wall-coated open tubular phases may not retain small molecules effectively. They are selected for gas analysis, light hydrocarbon profiling, and specialized separations requiring porous adsorption behavior.

• Permanent gases and very light hydrocarbons
• Gas analysis requiring strong retention of small molecules
• Specialty separations that benefit from porous adsorption

Practical note: PLOT columns are application-specific and often require method tuning for carrier gas, flow, and oven programs.