ZORBAX Eclipse XDB
Agilent ZORBAX Eclipse XDB HPLC Columns
Agilent ZORBAX Eclipse XDB columns are engineered for robust, high-performance separations across a wide pH range. Featuring Agilent’s proprietary eXtra Dense Bonding (XDB) and double endcapping, these columns deliver excellent peak shape for basic, acidic, and neutral compounds—making them a reliable, all-purpose choice for routine and advanced LC method development.
With four distinct reversed-phase selectivities (C8, C18, Phenyl-Hexyl, and CN), Eclipse XDB columns allow rapid optimization of retention and resolution. Their rugged bonded phases maintain consistent performance from pH 2 to 9, enabling durable operation under acidic and moderately basic conditions.
Available in particle sizes from 1.8 µm to 7 µm, Eclipse XDB columns support UHPLC, Rapid Resolution LC, and conventional HPLC systems—ensuring easy method transfer and scalability for pharmaceutical, environmental, food safety, and chemical analysis workflows.
Built on Agilent’s ultra-pure, high-efficiency silica, Eclipse XDB columns deliver durability, reproducibility, and chromatographic confidence across a wide variety of analytes and matrices.
XDB (eXtra Dense Bonding)
A highly stable bonding technology used in Eclipse XDB columns to improve durability, extend column lifetime, and maintain consistent performance across a wide pH range.
Double Endcapping
A secondary treatment that reduces residual silanol activity, improving peak shape—especially for basic analytes—and enhancing reproducibility.
Reversed-Phase Chromatography (RP)
A separation mode using hydrophobic stationary phases such as C18 or C8. Ideal for small molecules, pharmaceuticals, and complex organic mixtures.
Particle Size
Eclipse XDB columns offer particle sizes from 1.8–7 µm, supporting high-resolution UHPLC methods as well as robust, routine HPLC workflows with predictable method transfer.
pH Stability Range
Eclipse XDB columns perform reliably from pH 2–9, enabling robust separations of acidic, basic, and neutral compounds under varied mobile-phase conditions.
What makes Agilent ZORBAX Eclipse XDB columns unique?
Eclipse XDB columns use eXtra Dense Bonding and double endcapping to deliver strong peak shape, extended lifetime, and broad selectivity—ideal for method development on pH 2–9.
Which particle size should I choose for my method?
Use 1.8 µm for fast UHPLC separations, 3.5–5 µm for standard HPLC methods, and larger particles like 7 µm for preparative or older LC systems where lower backpressure is required.
Are Eclipse XDB columns compatible with acidic, basic, and neutral analytes?
Yes. The bonded-phase stability and double endcapping deliver excellent peak shape for analytes of all types, making Eclipse XDB phases highly versatile across multiple application spaces.
Product List
| SKU | Name | LC Column Phase | Particle Size | Inner Diameter (ID) | Length |
|---|---|---|---|---|---|
SKU
924975-302
|
Name
924975-302 - Eclipse XDB-C18 3.0 x 30 mm
|
LC Column Phase
Eclipse XDB-C18
|
Particle Size
1.8 um
|
Inner Diameter (ID)
3 mm
|
Length
30 mm
|
SKU
924700-906
|
Name
924700-906 - Eclipse XDB-C8,2.1x30mm,1.8um,600bar
|
LC Column Phase
Eclipse XDB-C8
|
Particle Size
1.8 um
|
Inner Diameter (ID)
2.1 mm
|
Length
30 mm
|
SKU
924700-902
|
Name
924700-902 - Eclipse XDB-C18 2.1 x 30 mm
|
LC Column Phase
Eclipse XDB-C18
|
Particle Size
1.8 um
|
Inner Diameter (ID)
2.1 mm
|
Length
30 mm
|
SKU
840140-901
|
Name
840140-901 - Semiprep Guard Hardware Kit
|
LC Column Phase
|
Particle Size
|
Inner Diameter (ID)
9.4 mm
|
Length
15 mm
|
SKU
823750-903
|
Name
823750-903 - UHPLC Grd, Ecl. XDB-C18,3.0mm,1.8um,3pk
|
LC Column Phase
Eclipse XDB-C18
|
Particle Size
1.8 um
|
Inner Diameter (ID)
3 mm
|
Length
5 mm
|
SKU
820999-901
|
Name
820999-901 - High performance ZORBAX guard fittings kit
|
LC Column Phase
|
Particle Size
|
Inner Diameter (ID)
4.6 mm
|
Length
12.5 mm
|
SKU
820950-935
|
Name
820950-935 - Eclipse XDB-CN Guard (4/pk), 4.6x12.5,5u
|
LC Column Phase
Eclipse XDB-CN
|
Particle Size
5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
13 mm
|
SKU
820950-927
|
Name
820950-927 - Eclipse XDB-Phenyl 4.6x12.5,5u 4PK
|
LC Column Phase
Eclipse XDB-Phenyl
|
Particle Size
5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
13 mm
|
SKU
820950-926
|
Name
820950-926 - Eclipse XDB-C8 Grd Crtds 4.6x12.5 4/PK
|
LC Column Phase
Eclipse XDB-C8
|
Particle Size
5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
13 mm
|
SKU
820950-925
|
Name
820950-925 - Eclipse XDB-C18 4.6x12.5,5u Grd Car 4/PK
|
LC Column Phase
Eclipse XDB-C18
|
Particle Size
5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
12.5 mm
|
SKU
821725-903
|
Name
821725-903 - UHPLC Guard, Eclipse XDB-C18, 1.8um, 3/pk
|
LC Column Phase
Eclipse XDB-C18
|
Particle Size
1.8 um
|
Inner Diameter (ID)
2.1 mm
|
Length
5 mm
|
SKU
821125-935
|
Name
821125-935 - Eclipse XDB-CN Guard (4/pk), 2.1x12.5,5u
|
LC Column Phase
Eclipse XDB-CN
|
Particle Size
5 um
|
Inner Diameter (ID)
2.1 mm
|
Length
13 mm
|