ZORBAX 80Å StableBond
Agilent ZORBAX 80Å StableBond HPLC Columns
- Industry-leading stability at low pH — engineered for long, reliable lifetimes in acidic mobile phases down to pH 1.
- Patented sterically protected siloxane bond delivers rugged performance under high temperature and harsh acidic conditions.
- Six bonded phases (SB-C18, SB-C8, SB-CN, SB-Phenyl, SB-C3, SB-Aq) provide broad selectivity for method development.
- High-purity Type B silica ensures sharp peaks, low bleed, and excellent reproducibility.
Agilent ZORBAX 80Å StableBond (SB) columns are the gold standard for low-pH reversed-phase separations. Built with patented nonfunctional silanes featuring bulky di-isobutyl or di-isopropyl side groups, the SB family sterically protects the critical siloxane bond from hydrolysis—ensuring unmatched stability where conventional silica columns rapidly degrade.
Because StableBond phases are not endcapped, they maintain maximum low-pH robustness and deliver highly reproducible retention for acids, bases, and neutrals. This makes the SB series ideal for pharmaceutical assays, stability-indicating methods, impurity profiling, and any workflow requiring extended operation at pH 1–2.
With six selectivity options and reliable performance across a wide range of temperatures and mobile phases, ZORBAX StableBond columns provide a dependable platform for accelerated method development and long-term routine analyses.
For guidance on choosing the best StableBond phase or exploring Chrom Tech’s full LC column portfolio, contact our technical specialists.
Low-pH Stability
The ability of a column to operate in strongly acidic mobile phases (down to pH 1) without phase loss or silica hydrolysis. StableBond columns are engineered specifically for long lifetime under these harsh conditions.
StableBond (SB) Chemistry
A patented Agilent bonding technology using nonfunctional silanes with bulky side groups that sterically shield the siloxane bond from hydrolytic attack, providing superior durability at low pH and elevated temperatures.
Bonded Phase Selectivity
The chromatographic selectivity created by surface chemistry (C18, C8, CN, Phenyl, C3, Aq). StableBond offers six distinct phases to tune interactions and optimize separation of acids, bases, neutrals, and polar analytes.
Type B Silica
High-purity silica with low metal content, resulting in improved peak shape for basic analytes and reduced secondary interactions—critical for reproducible, high-efficiency separations.
Non-Endcapped Phase
StableBond columns intentionally skip endcapping to maximize low-pH durability and stability, creating stronger bonding and reproducibility under acidic mobile phase conditions.
What makes ZORBAX StableBond columns ideal for low-pH separations?
StableBond columns use patented sterically protected alkyl silanes that shield the silica surface from hydrolytic attack, enabling long lifetimes and exceptional reproducibility even at pH 1 and elevated temperatures.
Are StableBond columns endcapped?
No. StableBond phases are intentionally non-endcapped to maximize their resistance to harsh acidic conditions and provide reproducible retention under aggressive mobile-phase environments.
Which bonded phases are available in the ZORBAX 80 Å StableBond family?
The StableBond family includes SB-C18, SB-C8, SB-C3, SB-Phenyl, SB-CN, and SB-Aq—offering broad selectivity and method-development coverage for acids, bases, neutrals, and high-aqueous workflows.
Can StableBond columns be used at high temperatures?
Yes. The patented bonding chemistry provides excellent thermal stability, making StableBond phases well-suited for fast, high-temperature LC methods without loss of performance.
Product List
| SKU | Name | LC Column Phase | Particle Size | Inner Diameter (ID) | Length |
|---|---|---|---|---|---|
SKU
835975-905
|
Name
835975-905 - SB-CN Rapid Res 3.5um,4.6x50mm HPLC Col
|
LC Column Phase
SB-CN
|
Particle Size
3.5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
50 mm
|
SKU
828700-914
|
Name
828700-914 - SB-Aq, 2.1x100mm, 1.8u, 600Bar
|
LC Column Phase
SB-Aq
|
Particle Size
1.8 um
|
Inner Diameter (ID)
2.1 mm
|
Length
100 mm
|
SKU
828700-912
|
Name
828700-912 - SB-Phenyl,2.1x100mm,1.8um,600bar
|
LC Column Phase
SB-Phenyl
|
Particle Size
1.8 um
|
Inner Diameter (ID)
2.1 mm
|
Length
100 mm
|
SKU
835975-902
|
Name
835975-902 - SB-C18 Rapid Res 3.5um,4.6x50mm HPLC Col
|
LC Column Phase
SB-C18
|
Particle Size
3.5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
50 mm
|
SKU
828700-906
|
Name
828700-906 - SB-C8,2.1X100MM,1.8UM,600bar
|
LC Column Phase
SB-C8
|
Particle Size
1.8 um
|
Inner Diameter (ID)
2.1 mm
|
Length
100 mm
|
SKU
828700-905
|
Name
828700-905 - SB-CN,2.1x100mm,1.8um,600bar
|
LC Column Phase
SB-CN
|
Particle Size
1.8 um
|
Inner Diameter (ID)
2.1 mm
|
Length
100 mm
|
SKU
823750-904
|
Name
823750-904 - UHPLC Grd, SB-C8, 3.0mm,1.8um,3pk
|
LC Column Phase
SB-C8
|
Particle Size
1.8 um
|
Inner Diameter (ID)
3 mm
|
Length
5 mm
|
SKU
834975-906
|
Name
834975-906 - SB-C8,4.6x30mm,1.8um,600bar
|
LC Column Phase
SB-C8
|
Particle Size
3.5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
30 mm
|
SKU
828700-902
|
Name
828700-902 - SB-C18 2.1 X 100 mm
|
LC Column Phase
SB-C18
|
Particle Size
1.8 um
|
Inner Diameter (ID)
2.1 mm
|
Length
100 mm
|
SKU
834975-902
|
Name
834975-902 - SB-C18,4.6x30mm,1.8um,600bar
|
LC Column Phase
SB-C18
|
Particle Size
3.5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
30 mm
|
SKU
823750-902
|
Name
823750-902 - UHPLC Grd, SB-C18,3.0mm, 1.8um,3pk
|
LC Column Phase
SB-C18
|
Particle Size
1.8 um
|
Inner Diameter (ID)
3 mm
|
Length
5 mm
|
SKU
820999-901
|
Name
820999-901 - High performance ZORBAX guard fittings kit
|
LC Column Phase
|
Particle Size
|
Inner Diameter (ID)
4.6 mm
|
Length
12.5 mm
|