Zirchrom

ProTain
In-Line Protein
Removal System
Zirconia
Zirconia-Based
HPLC Columns

ZirChrom HPLC Columns

Unique Selectivity, Unparalleled Stability

ZirChrom HPLC columns feature stationary phases engineered from porous zirconia particles that deliver exceptional chemical and thermal stability, outperforming traditional silica-based columns under extreme pH and temperature conditions.

These monodisperse 3 µm zirconia spheres are produced through controlled polymerization-induced aggregation of 1000 Å colloidal zirconia and sintered at temperatures exceeding 900 °C to achieve a robust monoclinic crystalline structure. This proprietary process ensures consistent performance, long column lifetimes, and outstanding reproducibility for challenging separations.

The ProTain In-Line Protein Removal System complements ZirChrom’s column line by enabling efficient protein elimination directly from biological samples, extending column longevity and maintaining reliable chromatographic performance.

Chrom Tech proudly supplies the full range of ZirChrom zirconia-based HPLC solutions, trusted by analytical laboratories requiring unmatched durability and selectivity. Contact Chrom Tech for expert assistance selecting the ideal column for your method.

Frequently Asked Questions

What makes zirconia-based HPLC columns different from silica-based columns?

Zirconia-based columns provide superior stability across extreme pH ranges and temperatures, resisting hydrolysis and chemical degradation that can shorten the lifespan of silica columns.

What applications are ideal for ZirChrom HPLC columns?

ZirChrom columns are ideal for bioanalytical, pharmaceutical, and environmental applications requiring high chemical resistance, rugged reproducibility, and unique selectivity under demanding chromatographic conditions.

How does the ProTain system improve protein analysis?

The ProTain In-Line Protein Removal System removes high-molecular-weight proteins prior to HPLC injection, preventing column fouling and extending operational life—especially beneficial for biological sample analysis.