Successful Strategies for the Analysis of EtG and EtS in Urine

In a report by the National Highway Traffic Administration, it was found that an alcohol-impaired driver was involved in nearly one-third of all traffic crash fatalities. Impaired driving can result in several various penalties. Often times, the courts will order substance abuse evaluations, which can include a drug and alcohol urinalysis screening.             

Ethyl glucuronide (EtG) and ethyl sulfate (EtS) are important biomarkers for monitoring alcohol use. For the court system, there are many advantages to using EtG and EtS, as a positive EtG result indicates that a person has recently been exposed to alcohol, up to three days, even when there is no longer ethanol detectable in the person’s system. According to Restek, EtG and EtS also provide good stability and analytical specificity, along with the long detection window.  

With the Restek Raptor EtG/EtS LC column, Restek has provided fast, 4-minute, dilute-and-shoot LC-MS/MS method that supports high sample throughput. Save time and increase certainty with the definitive EtG/EtS method.

Chrom Tech is a Minnesota-based, worldwide distributor of chromatography instrumentation and supplies and mass spectrometry supplies. We carry vials, well plates, syringe filters, solvent waste containers and all other critical chromatography and spectrometry supplies. Contact Chrom Tech  to become your preferred supplier of chromatography and mass spectrometry supplies.