Silanized Vials

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Silanized Chromatography Vials

Because the surface of laboratory glassware is slightly acidic, it can adsorb some analytes — particularly amines. In low level analyses, such losses can be significant. To prevent sample loss through adsorption, glassware used in low level analyses usually is silanized. Silanization masks the polar Si-OH groups on the glass surface by chemically binding a nonadsorptive silicone layer to the surface, in effect “derivatizing” the glass.