Rtx-5MS

Rtx-5MS column

Restek Rtx-5MS GC Columns

Restek Rtx-5MS GC columns are engineered specifically for GC-MS applications requiring extremely low bleed, exceptional inertness, and reliable performance across a wide range of analytes. Featuring a 5% diphenyl, 95% dimethylpolysiloxane stationary phase, Rtx-5MS columns provide balanced selectivity for both polar and nonpolar compounds while maintaining the high thermal stability needed for demanding MS workflows.

Their MS-grade deactivation chemistry minimizes active sites within the tubing, resulting in sharp, symmetrical peak shapes for acids, bases, semi-volatiles, pesticides, PAHs, aromatics, and reactive functionalized analytes. The extremely low bleed levels contribute to cleaner mass spectra, reduced background noise, and improved detection limits—even during high-temperature programs.

Rtx-5MS columns exhibit excellent batch-to-batch reproducibility, making them a dependable choice for validated methods, forensic toxicology, environmental analysis, and industrial QC workflows. They are fully compatible with GC-FID, GC-MS, and GC-MS/MS instrumentation, supporting both qualitative and quantitative applications.

Chrom Tech, as an authorized Restek distributor, offers Rtx-5MS columns in a broad range of lengths, inner diameters, and film thicknesses to support laboratories needing consistent, high-sensitivity separations with the durability and reproducibility expected from an MS-grade capillary GC column.
Key Definitions ▸
MS-Grade Low Bleed
Ultra-low stationary-phase bleed designed for mass spectrometry, providing cleaner spectra and improved detection limits during high-temperature operation.
5% Diphenyl / 95% Dimethyl Polysiloxane
A low-polarity phase that provides broad applicability while enhancing the separation of aromatic, semi-volatile, and moderately polar compounds.
Inertness for Reactive Analytes
Specialized column deactivation prevents adsorption of acidic, basic, or highly functionalized analytes, ensuring reproducible peak shape and quantitation.
Thermal Stability
The ability to operate at elevated temperatures required for GC-MS workflows without significant degradation or bleed, supporting long-term durability.
Validated-Method Reproducibility
Strict manufacturing controls ensure consistent retention times and selectivity from column to column, supporting regulated GC-MS applications.
Frequently Asked Questions ▸
What applications are Rtx-5MS columns best suited for?
They are ideal for GC-MS analysis of semi-volatiles, pesticides, PAHs, drugs of abuse, VOCs, and general organic compounds requiring sharp peak shapes and low background noise.
How does Rtx-5MS differ from standard Rtx-5 columns?
Rtx-5MS columns feature MS-grade deactivation and much lower bleed, making them specifically suitable for sensitive GC-MS workflows requiring cleaner baselines and better detection limits.
Can Rtx-5MS columns be used with both GC-FID and GC-MS?
Yes. While optimized for MS, they also provide excellent response and peak shape with FID, ECD, and other GC detectors.
Do Rtx-5MS columns support trace-level quantitation?
Absolutely—these MS-grade columns provide sharp peaks, extremely low bleed, and strong inertness, supporting trace and ultra-trace detection levels in complex GC-MS workflows.