Rtx-2330

Rtx-2330 column

Restek Rtx-2330 GC Columns

Restek Rtx-2330 GC columns are highly polar cyanopropyl-containing phases specifically engineered for the detailed resolution of structural, geometric, and positional isomers—particularly fatty acid methyl esters (FAMEs). The stationary phase features a 90% biscyanopropyl, 10% cyanopropylphenyl polysiloxane chemistry, making Rtx-2330 one of the most polar GC phases in the Restek portfolio. This level of polarity enables unmatched selectivity for complex mixtures where analytes share similar boiling points but differ in subtle structural features.

Rtx-2330 excels at resolving cis/trans FAME isomers, short- through long-chain FAMEs, and challenging positional variants that require extremely high separation efficiency. Its superior isomer resolution is widely used in food and nutritional research, biodiesel characterization, lipid profiling, forensic investigations, and other analytical workflows involving fatty acids or structurally complex polar analytes.

The column’s strong polar functionality enhances dipole and hydrogen-bonding interactions, providing highly structured elution patterns and stable retention behavior. With robust deactivation chemistry, low bleed, and excellent thermal stability for such a polar phase, Rtx-2330 supports both GC and GC-MS workflows requiring precise, reproducible separation of intricate isomeric mixtures.

As an authorized Restek distributor, Chrom Tech supplies Rtx-2330 columns in a variety of lengths, IDs, and film thicknesses—ensuring laboratories can achieve the highest resolution possible for fatty acid and isomer-specific analyses.

Key Definitions
90% Biscyanopropyl Stationary Phase
One of the highest-polarity GC phases available, providing exceptional selectivity for geometric, positional, and structural isomers—especially in complex FAME mixtures.
FAME Isomer Resolution
The ability to separate cis/trans, positional, and chain-length variants of fatty acid methyl esters. Rtx-2330 is specifically designed to provide the highest level of separation efficiency for these challenging analytes.
Isomeric Compound Selectivity
Rtx-2330’s high polarity enhances interactions that allow precise separation of structurally similar analytes, supporting detailed characterization of complex mixtures.
Dipole & Hydrogen-Bonding Retention
The retention mechanism that allows Rtx-2330 to strongly interact with polar analytes, markedly improving separation of analytes with minimal boiling-point differences.
Rtx® Deactivation
A specialized surface treatment designed to minimize active sites within the column, ensuring retention stability and sharp peaks for highly polar and reactive compounds even on this extremely polar phase.
Frequently Asked Questions
What makes Rtx-2330 ideal for FAME analysis?
Its extremely high polarity and dual cyanopropyl functionality provide superior resolution of cis/trans, structural, and positional FAME isomers—critical for food, nutrition, and biodiesel research.
Is Rtx-2330 suitable for GC-MS?
Yes. Despite its high polarity, Rtx-2330 offers low bleed and strong inertness, allowing accurate GC-MS analysis of complex, polar mixtures including detailed FAME profiles.
Which industries commonly use Rtx-2330 columns?
Food and nutritional science, biodiesel production, lipid profiling, environmental research, and forensic laboratories performing complex isomeric separations all rely on Rtx-2330.
How does Rtx-2330 compare to Rtx-225 or Rtx-200?
Rtx-2330 is significantly more polar, offering the highest isomer-resolution capability in the series. Rtx-225 and Rtx-200 offer strong polarity but are not optimized for the extreme isomer separations achieved by Rtx-2330.