6th Jan 2025
Reduce Instrument Downtime with Sample Preparation
Minimizing downtime in the laboratory not only saves valuable time but also reduces the costs associated with getting instruments back in operation. A simple way to reduce HPLC downtime is by extending the lifespan of HPLC columns, reducing the need for frequent replacements. Proper sample preparation plays a key role in achieving optimal chromatography and also contributes to longer column life by preventing excess particulates from entering the system. Additionally, using inline filters and guard columns can help capture particulates before they reach the analytical column. These components are more affordable and easier to replace than analytical columns, helping to protect your equipment and maintain efficient operation.
What Sample Prep Methods are Best?
There are a variety of sample preparation methods from ‘dilute and shoot’ to SLE or LLE. Some sample preparation methods are better for certain applications than others. Filtration is an easy and inexpensive way to reduce particulates in a sample by passing the sample through a membrane. The larger particles won’t pass through, leaving a cleaner sample to inject. We offer numerous filtration options, so you can use the best option for your specific applications. Centrifuge filter tubes are commonly used as an inexpensive and quick way to filter multiple samples at once. If you’re just planning to filter a few samples at a time, syringe filters are another economical option and are quite simple to use. Plus we always keep them in stock and ready to ship. One other popular filtration option is our Filter Vials, which eliminates the need for multiple transfer steps of the sample. The autosampler friendly filter vials have a filter, an autosampler vial, and a cap all in one simple to use design.
Conclusion
If your workflow is missing a sample preparation step, reach out to our team of chromatography experts to find out what method may work best for your analysis. Sample preparation will improve your analysis by providing cleaner samples for better chromatography and longer column lifetime.