Organic GPC/SEC Columns

Agilent Organic GPC/SEC HPLC Columns

Agilent Organic GPC/SEC columns deliver industry-leading performance for the characterization of polymers, plastics, resins, and other macromolecules in organic solvents. Built on Agilent’s proven PLgel technology, these columns provide exceptional resolution, long-term stability, and highly reproducible molecular-weight determinations across a wide analytical range.

The PLgel series is globally recognized for its rugged fully porous gel matrix, extensive pore-size options, and compatibility with common organic GPC/SEC solvents such as THF, toluene, chlorobenzene, and DMF. With tailored selectivities, high column efficiency, and reliable calibration curves, PLgel columns support routine QC through advanced R&D applications.

Chrom Tech offers the complete portfolio of Agilent Organic GPC/SEC solutions, ensuring you have the right particle size, pore size, and hardware configuration to achieve accurate, repeatable polymer analysis—no matter the complexity of your sample.

Key Definitions

Gel Permeation Chromatography (GPC)

A size-based separation technique performed in organic solvents. GPC is widely used for molecular-weight distribution analysis of polymers, plastics, additives, and resins.

Size Exclusion Chromatography (SEC)

A chromatographic method that separates molecules based on hydrodynamic size. In organic SEC (GPC), larger polymer species elute earlier than smaller ones due to reduced pore access.

PLgel Packing Material

Agilent’s high-performance, cross-linked polystyrene-divinylbenzene (PS-DVB) packing used in PLgel GPC columns. These materials offer exceptional mechanical, chemical, and thermal stability across a wide range of organic solvents.

Pore Size (Å)

The diameter of pores within the particle packing. Larger pore sizes enable separation of high-molecular-weight polymers, while smaller pore sizes suit oligomers and lower-mass materials.

Mixed-Bed Columns

Columns containing a blend of pore sizes to provide a wide molecular-weight calibration range. Mixed-bed GPC/SEC columns are commonly used for unknown or broad polymer distributions.

Frequently Asked Questions

What are Agilent Organic GPC/SEC columns typically used for?

These columns are used for determining molecular weight distribution and polymer characterization in organic solvents. They are essential in analyzing plastics, synthetic polymers, elastomers, and other hydrophobic macromolecules.

What makes Agilent PLgel columns an industry standard?

Agilent PLgel columns offer precise pore-size control, robust mechanical stability, and excellent chemical compatibility. Their consistent lot-to-lot reproducibility ensures highly reliable GPC/SEC results across laboratories.

Are multiple pore sizes available for different polymer types?

Yes. The PLgel family includes a wide range of pore sizes to match specific molecular weight ranges—from low-molecular-weight oligomers to ultra-high-molecular-weight polymers—allowing optimized resolution for each application.

Are Agilent Organic GPC/SEC columns compatible with all organic solvents?

Yes. PLgel columns are engineered for full compatibility with common organic solvents such as THF, toluene, DMF, and chlorinated solvents, making them ideal for polymer laboratories with diverse method requirements.

Product List

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SKU Name Type Guard Column Inner Diameter (ID) Length
SKU
PL1110-6120
Name
PL1110-6120 - PLgel 10um 100A 300 x 7.5 mm
Type
HPLC Column
Guard Column
No
Inner Diameter (ID)
7.5 mm
Length
300 mm
SKU
PL1210-6160
Name
PL1210-6160 - PLgel 10um 10E6A 300 x 25 mm
Type
HPLC Column
Guard Column
No
Inner Diameter (ID)
25 mm
Length
300 mm
SKU
PL1113-1300
Name
PL1113-1300 - ResiPore Guard 50 x 7.5 mm
Type
Guard
Guard Column
Yes
Inner Diameter (ID)
7.5 mm
Length
50 mm
SKU
PL1110-6115
Name
PL1110-6115 - PLgel 10um 50A 300 x 7.5 mm
Type
HPLC Column
Guard Column
No
Inner Diameter (ID)
7.5 mm
Length
300 mm
SKU
PL1210-6150
Name
PL1210-6150 - PLgel 10um 10E5A 300 x 25 mm
Type
HPLC Column
Guard Column
No
Inner Diameter (ID)
25 mm
Length
300 mm
SKU
PL1110-6100LS
Name
PL1110-6100LS - PLgel 10um MIXED-B LS 300 x 7.5 mm
Type
HPLC Column
Guard Column
No
Inner Diameter (ID)
7.5 mm
Length
300 mm
SKU
PL1210-6140
Name
PL1210-6140 - PLgel 10um 10E4A 300 x 25 mm
Type
HPLC Column
Guard Column
No
Inner Diameter (ID)
25 mm
Length
300 mm
SKU
PL1110-6100
Name
PL1110-6100 - PLgel 10um MIXED-B 300 x 7.5 mm
Type
HPLC Column
Guard Column
No
Inner Diameter (ID)
7.5 mm
Length
300 mm
SKU
PL1210-6130
Name
PL1210-6130 - PLgel 10um 10E3A 300 x 25 mm
Type
HPLC Column
Guard Column
No
Inner Diameter (ID)
25 mm
Length
300 mm
SKU
PL1110-1520
Name
PL1110-1520 - PLgel 5um Guard 50 x 7.5 mm
Type
Guard
Guard Column
Yes
Inner Diameter (ID)
7.5 mm
Length
50 mm
SKU
PL1210-6125
Name
PL1210-6125 - PLgel 10um 500A 300 x 25 mm
Type
HPLC Column
Guard Column
No
Inner Diameter (ID)
25 mm
Length
300 mm
SKU
PL1110-1400
Name
PL1110-1400 - PLgel Olexis Guard 50 x 7.5 mm
Type
Guard
Guard Column
Yes
Inner Diameter (ID)
7.5 mm
Length
50 mm