Ion Analysis

Concise Separations Columns for Ion Analysis

  • Rugged polymeric substrate with full pH stability from 0 to 14
  • Excellent solvent compatibility for flexible IC method development
  • High column efficiency for sharp, well-resolved anion peaks
  • Reliable lot-to-lot and column-to-column reproducibility
  • Strong anion-exchange chemistry ideal for comprehensive anion profiling

Concise Separations ion chromatography (IC) columns are engineered for robust, reproducible ion analysis across a wide range of IC systems. Built on a durable polymeric substrate with exceptional chemical stability, these columns maintain performance over aggressive pH conditions, enabling consistent retention and long operational lifetimes.

Each column is optimized for high-efficiency anion separations using strong anion-exchange functional groups that deliver reliable peak shape, selectivity, and resolution. Their broad solvent compatibility supports diverse eluent systems, allowing analysts to tailor IC conditions for environmental, industrial, and regulatory applications.

Concise Separations IC columns are fully tested for compatibility with Metrohm, Dionex, Hach–Lachat, Alltech, and other major IC platforms. Their selectivities align with widely used industry standards, including methods specified in EPA 300 (Parts A and B) and EPA 300.1, ensuring seamless method transfer and regulatory compliance.


Column Competitive Columns Application Recommended Eluents Comments
ICSep AN300 Dionex AS4A F-, Cl-, NO2-, Br-, NO3-, HPO42-, SO42-. EPA Method 300.0(a) Carbonate Good for drinking water method, EPA 300.0 or 300.1. Superb fluoride separation from water dip and other anions. Fast analysis times (under 9 min for 7 std anions)
ICSep AN1 Dionex AS9-HC F-, Cl-, NO2-, Br-, NO3-, HPO42-, SO42-. Low MW organic acids in medium to high ionic strength matrices. Cr(III), Cr(VI) as CrO3-, CrO42- Carbonate Can be used with non-suppressed conductivity detection. Very good fluoride separation from water dip. Great for toothpaste analysis. Excellent trace anion work.
ICSep AN1SC Dionex AS9-HC F-, Cl-, NO2-, Br-, NO3-, HPO42-, SO42-. Low MW organic acids in medium to high ionic strength matrices Solvent compatible Similar selectivity to AN1 but solvent compatible for easy cleanup
ICSep AN2 Dionex AS14 Arsenate, sulfite, selenate, arsenite, selenite, F-, Cl-, NO2-, Br-, NO3-, HPO42-, SO42-. Low MW organic acids Sodium hydroxide eluents Superb fluoride, acetate & chloride resolution
ICSep AN300B Dionex AS9 F-, Cl-, NO2-, Br-, NO3-, HPO42-, SO42-, ClO2-, ClO3-, BrO3- Solvent compatible Good for drinking water method, EPA 300.0(b) for oxyhalides. High capacity & unique selectivity
ICSep ION-120   F-, Cl-, NO2-, Br-, NO3-, HPO42-, SO42-. Low MW organic acids in medium to high ionic strength matrices. Cr(III), Cr(VI) Salicylic acid Very good for non-suppressed detection. Fast analysis. No conductivity cell required (UV)
ICSep AN-SDA   F-, Cl-, NO2-, Br-, NO3-, HPO42-, SO42-. Low MW organic acids. Cr(III), Cr(VI) Solvent compatible Created for phosphate & anions in soft drinks. No dilution needed. Colorings & additives will not foul column.
AN1-SS Alltech A-2 F-, Cl-, NO2-, Br-, NO3-, HPO42-, SO42-. EPA Method 300.0(a) Solvent compatible Designed to replace Alltech A-2 anion column
AN1-HS   F-, Cl-, NO2-, Br-, PO4, SO4 Carbonate Fast AN1 column with sulfate detection under four minutes
AN2-HC   All inorganic anions including oxyhalides and low MW organic acids Solvent compatible Ideal for tough separations. Extra capacity improves resolution. Superb fluoride, acetate & chloride resolution.
AN300BHS   For simple samples containing oxyhalides Solvent compatible Fast AN300B column with sulfate under six minutes. Resolves oxyhalides. High throughput.
ICSep AN300H   F-, Cl-, NO2-, Br-, NO3-, HPO42-, SO42-. EPA Method 300.0(a) Carbonate Very high capacity AN300 column. Excellent for tough separations. Superb resolution with quick retention. Ideal for drinking water (EPA 300.0/300.1). Handles high Cl or NO3 loads.
DESCRIPTION SIZE AN2 AN1 AN1-SC AN300 AN300B
PEEK Column 5.5 x 150 mm – – – ANX-99-7620 –
PEEK Column 4.6 x 250 mm ANX-99-8515 ANX-99-8511 ANX-99-8514 – ANX-99-8516
Guard Cartridges (3/pk)   ANX-99-0015 ANX-99-0010 ANX-99-0014 ANX-99-0010 ANX-99-0016
Guard Column   ANX-99-3515 ANX-99-3510 ANX-99-3514 ANX-99-3510 ANX-99-3516
Replacement Frits (5/pk)   AXC-99-0012 AXC-99-0012 AXC-99-0012 AXC-99-0012 AXC-99-0012
Guard Disc® (5/pk)   GRD-99-0703 GRD-99-0703 GRD-99-0703 GRD-99-0703 GRD-99-0703
Cartridge Kit (Column, Guard Cartridges (3/pk), Column Coupler & Guard Cartridge Holder)   ANX-99-8545K ANX-99-8541K ANX-99-8544K ANX-99-7643 ANX-99-8546K
Column Kit (Column, Guard Column & Column Coupler)   ANX-99-8535K ANX-99-8531K ANX-99-8534K ANX-99-7633 ANX-99-8536K
DESCRIPTION SIZE AN-SDA AN1-SS AN1-HS AN2-HC AN300BHS AN300H
PEEK Column 4.6 x 200 mm – – – ANX-99-8518 – –
PEEK Column 4.6 x 150 mm – – – – – ANX-99-4650
PEEK Column 4.6 x 50 mm ANX-99-4650 – ANX-99-3518 – ANX-99-3566 –
SS Column 4.6 x 100 mm – ANX-99-5518S – – – –
Guard Cartridges (3/pk)   – – – ANX-99-0018 – ANX-99-0010
Guard Column   – – – ANX-99-3517 – ANX-99-3510
Replacement Frits (5/pk)   – – AXC-99-0012 AXC-99-0012 AXC-99-0012 AXC-99-0012
Guard Disc® (5/pk)   – – GRD-99-0703 GRD-99-0703 GRD-99-0703 GRD-99-0703
Cartridge Kit (Column, Guard Cartridges (3/pk), Column Coupler & Guard Cartridge Holder)   – – – ANX-99-8548K – –
Column Kit (Column, Guard Column & Column Coupler)   – – – ANX-99-8538K – –

Key Definitions â–¸
Ion Chromatography (IC)
A chromatographic technique used to separate and quantify anions and cations using ion-exchange mechanisms. IC is widely applied in environmental monitoring, water quality analysis, and regulatory compliance testing.
Strong Anion Exchange (SAX)
A stationary phase chemistry featuring strongly basic functional groups that retain negatively charged analytes. SAX columns provide high selectivity for inorganic and organic anions across a wide concentration range.
pH Stability (0–14)
The ability of a polymeric column substrate to withstand highly acidic and highly basic eluent conditions without degrading, enabling aggressive cleaning and flexible IC method development.
EPA Method 300 / 300.1
U.S. Environmental Protection Agency methods describing approved ion chromatography procedures for measuring inorganic anions in drinking water and wastewater, ensuring regulatory compliance for public health and safety testing.
Solvent Compatibility
The ability of an IC column to withstand a variety of aqueous eluents and conditioning solvents without compromising performance, enabling broader application flexibility.
Frequently Asked Questions â–¸

What makes Concise Separations IC columns suitable for ion analysis?

These columns combine strong anion-exchange chemistry, high efficiency, and polymeric durability across the full pH 0–14 range. Their performance is optimized for reliable anion separation on major IC platforms.

Are these columns compatible with my ion chromatography system?

Yes. Concise Separations IC columns are validated for use on Metrohm, Dionex, Hach–Lachat, Alltech, and many other IC instruments, ensuring broad compatibility and smooth method transfer.

Can these columns be used for EPA Method 300 / 300.1?

Yes. Their selectivities and performance characteristics align with EPA 300 and EPA 300.1 requirements for inorganic anion analysis in drinking water, wastewater, and environmental samples.