Hamilton

Hamilton HPLC Columns

Hamilton HPLC columns are engineered with advanced polymeric stationary phases that deliver exceptional durability, chemical resistance, and long lifetime performance under demanding analytical conditions. With over 35 years of innovation, Hamilton remains a leader in polymer-based chromatography solutions.

The Hamilton portfolio includes reversed-phase, anion-exchange, cation-exchange, and ion-exclusion columns designed for reproducible retention, sharp peak symmetry, and stable performance across wide pH and temperature ranges. These polymeric chemistries excel in applications requiring rugged operation, method consistency, and resistance to aggressive eluents.

Chrom Tech supplies the full line of Hamilton HPLC columns and accessories, supported by expert technical guidance and fast U.S. fulfillment—helping laboratories achieve precise, reliable separations for environmental, food, pharmaceutical, and industrial analyses.

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Hamilton HPLC Column Categories

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Key Definitions ▸
Polymeric Stationary Phase
A highly durable, chemically resistant chromatographic substrate used in Hamilton columns, offering superior stability across wide pH ranges and extended lifetimes compared to silica-based media.
Ion-Exclusion Chromatography
A separation mode used for organic acids, where non-ionized species penetrate the stationary phase while ionic species are excluded, delivering strong resolution for weak acids in aqueous systems.
Anion Exchange Chromatography
A mode where negatively charged analytes bind to positively charged functional groups on the stationary phase, enabling selective elution based on ionic strength or pH.
Cation Exchange Chromatography
A technique where positively charged analytes interact with negatively charged stationary-phase groups, enabling controlled separation of metal ions, amines, and other cationic species.
Reversed-Phase Chromatography
A widely used LC mode where non-polar analytes interact with hydrophobic polymeric surfaces, providing predictable retention and strong peak symmetry across diverse sample types.
Frequently Asked Questions ▸
What makes Hamilton HPLC columns unique?
Hamilton columns use proprietary polymeric stationary phases that resist extreme pH, aggressive solvents, and high mechanical stress—providing long lifetimes and highly reproducible separations across demanding applications.
What types of separations are Hamilton columns suitable for?
Hamilton offers reversed-phase, anion-exchange, cation-exchange, and ion-exclusion columns designed for environmental, food, pharmaceutical, biochemical, and industrial applications.
Are Hamilton polymeric columns compatible with extreme pH conditions?
Yes. Hamilton’s polymeric stationary phases maintain structural integrity across a wide pH range, often outperforming silica-based media in harsh chemical environments or routine high-pH workflows.
Can Hamilton HPLC columns replace silica-based columns?
In many cases, yes. Their polymeric design provides enhanced pH stability, improved chemical resistance, and long-term reproducibility, making them strong alternatives to silica columns in harsh or routine separations.