Filter Vials

  • Integrated filter, vial, and cap—one streamlined device
  • Simple press-down operation—no tools required

Thomson Filter Vials eliminate multi-step sample transfers by combining filtration and sample containment in a single, convenient device. Each filter vial includes a pre-slit cap (excluding low-evaporation caps) for clean aliquot withdrawal without needle breakage or coring—helping reduce the risk of autosampler interruptions and costly instrument downtime.

Designed for compatibility with most standard HPLC and LC/MS autosamplers, these vials make filtration fast, clean, and repeatable. The push-down design supports consistent sample processing, making filter vials a practical solution for analytical and research labs.

Protein Crash Simplified

Protein precipitation prior to HPLC analysis is often performed offline using separate equipment. Thomson PTFE Filter Vials streamline this workflow by allowing protein crash and filtration in one step— mixing acetonitrile and aqueous solution directly in the bottom chamber. As the filter is pressed down, proteins are trapped while the clean filtrate passes through, ready for injection.

MEMBRANE PORE SIZE CAP COLOR STANDARD EXTREME NANO
THOMSON FILTER VIALS (100/PK)
Nylon0.2 µmBlack FV-1020 FV-1020EX FV-1020N
Nylon0.45 µmPink FV-1045 FV-1045EX —
PTFE0.2 µmGreen FV-2020 FV-2020EX FV-2020N
PTFE0.45 µmBlue FV-2045 FV-2045EX FV-2045N
PVDF0.2 µmRed FV-3020 FV-3020EX FV-3020N
PVDF0.45 µmYellow FV-3045 FV-3045EX FV-3045N
PES0.2 µmGrey FV-6020 FV-6020EX FV-6020N
Standard & Extreme: Pre-slit PTFE/Silicone Septa Snap Cap attached to a Plunger Filter, outside PP shell vial (250 µL dead volume, 450 µL max volume).
Nano: Pre-slit PTFE/Silicone Septa Snap Cap attached to a Plunger Filter, outside PP shell vial (10 µL dead volume, 250 µL max volume).
Tech Tip | Thomson Filter Vial & Protein Crash

Protein samples need to be crashed out before injecting them into the HPLC. Many people have traditionally done off line crash procedures. The Thomson PTFE Filter Vials can do this easily by mixing the acetonitrile and aqueous solution in the bottom chamber, and then allowing the filter to push down trapping the protein, and letting the clean sample come through for analysis.

Key Definitions ▸
Filter vial
A single device that combines filtration and sample containment so the filtrate collects directly in a vial that can be placed into an autosampler without additional transfers.
Press-down filtration
A simple filtration method where the filter insert is pushed down through the sample chamber, forcing liquid through the membrane and collecting clean filtrate below—no syringe required.
Pre-slit cap
A vial cap designed with a slit that allows easy needle penetration and aliquot withdrawal while minimizing coring and helping reduce needle damage during autosampler use.
PTFE membrane
A chemically resistant filter membrane material commonly used for aggressive solvents and demanding sample prep, including workflows where protein precipitation and solvent exposure are factors.
Protein crash
A sample prep technique that uses an organic solvent (commonly acetonitrile) to precipitate proteins so they can be removed prior to HPLC or LC/MS analysis, helping protect columns and improve data quality.
Frequently Asked Questions ▸
What makes Thomson Filter Vials different from traditional filtration methods?
Thomson Filter Vials combine the filter, vial, and cap in one device—removing the need for syringes, membranes, or transfer steps. This design reduces contamination risk and improves workflow efficiency.
Are Thomson Filter Vials compatible with my autosampler?
Yes. Thomson Filter Vials are designed to fit most standard HPLC and LC/MS autosamplers without modification or additional adapters.
Can Thomson Filter Vials be used for protein crash preparation?
Absolutely. The PTFE-filter version allows protein crash and filtration in one step by mixing acetonitrile and aqueous phases, trapping proteins while collecting a clean, ready-to-analyze filtrate.