DB-5.625

DB-5.625 column

Agilent DB-5.625 GC Columns

Agilent J&W DB-5.625 GC columns are engineered to provide balanced, versatile selectivity for the analysis of a wide range of semivolatile organic compounds (SVOCs), including halogenated solvents, pesticides, phenols, phthalates, nitrosamines, and other regulated contaminants. With a unique mid-polarity stationary phase, DB-5.625 bridges the gap between traditional nonpolar and highly polar phases—making it ideal for broad-scope environmental, industrial, and regulatory applications where multiple compound classes must be accurately resolved in a single analysis.

The proprietary 5%-phenyl/95%-methyl polysiloxane phase infused with a specialized cyanopropyl component enhances separation of halogenated SVOCs, improving resolution for analytes that commonly co-elute on standard 5-type columns. DB-5.625 also delivers strong thermal stability and low bleed, ensuring clean baselines and dependable mass spectrometric sensitivity for trace-level quantitation.

As an authorized distributor of Agilent GC columns, Chrom Tech offers DB-5.625 as a high-performance, multiuse solution favored in EPA, state, and global regulatory testing programs. Its combination of ruggedness, reproducibility, and balanced selectivity makes it a reliable choice for laboratories handling complex semivolatile mixtures across diverse sample matrices.
Key Definitions â–¸
DB-5.625
A mid-polarity GC column designed for broad-spectrum semivolatile analysis. DB-5.625 provides balanced selectivity for halogenated and non-halogenated SVOCs, making it ideal for environmental and industrial testing where multiple compound classes must be analyzed in a single run.
Mid-Polarity Phase
A stationary phase that incorporates both nonpolar and polar functional groups. The DB-5.625 phase includes a cyanopropyl component that improves separation of halogenated semivolatile compounds compared to standard 5%-phenyl phases.
Semivolatile Organic Compounds (SVOCs)
Medium- to high-boiling organic compounds such as PAHs, phenols, phthalates, nitrosamines, halogenated solvents, pesticides, and dioxins. Their diverse chemical structures require GC columns with optimized selectivity and thermal stability for accurate analysis.
Cyanopropyl Functional Group
A moderately polar functional group incorporated into the DB-5.625 stationary phase to enhance interactions with halogenated organic compounds. This improves resolution of mixed semivolatile analytes compared to traditional nonpolar GC phases.
Frequently Asked Questions â–¸
What makes the DB-5.625 column different from a standard DB-5 column?
DB-5.625 incorporates a cyanopropyl component that increases mid-polarity selectivity, improving separation of halogenated semivolatile compounds. This makes DB-5.625 more effective for complex mixtures where nonpolar phases like DB-5 may not provide sufficient resolution.
What applications commonly use DB-5.625 GC columns?
DB-5.625 is widely used in environmental, industrial, and regulatory testing, including EPA-driven SVOC analysis, pesticides, phthalates, phenols, nitrosamines, and halogenated solvents. Its balanced selectivity supports multi-class compound analysis in a single run.
Does DB-5.625 provide low bleed for MS detection?
Yes. DB-5.625 is designed to maintain low bleed even at elevated temperatures, ensuring stable baselines and strong MS sensitivity for trace-level quantitation of semivolatile organic compounds.