Aqueous GPC/SEC Columns
HPLC Columns for Aqueous GPC and SEC Analyses
Chrom Tech supplies the full portfolio of Agilent aqueous GPC and SEC columns designed for precise molecular weight characterization of polymers, plastics, biomolecules, and hydrophilic materials. The industry-leading PL aquagel-OH and PolarGel families deliver reliable separations in water, buffers, and polar solvent systems, making them ideal for environmentally friendly and biocompatible workflows.
Engineered for stability, low swelling, and exceptional batch-to-batch reproducibility, these columns offer a wide range of pore sizes, particle sizes, and hardware formats to match any analytical requirement—from routine QC to advanced research on complex polymer architectures. Their optimized hydrophilic stationary phases help ensure accurate calibration curves, consistent retention, and dependable long-term performance.
Whether you are characterizing natural polymers, synthetic hydrogels, polysaccharides, water-soluble plastics, or other macromolecules, Agilent’s aqueous GPC/SEC solutions provide the resolution, durability, and flexibility needed for high-confidence results across modern polymer labs.
Gel Permeation Chromatography (GPC)
A size-based separation technique where larger molecules elute earlier because they are excluded from the pores of the stationary phase. Commonly used for polymer molecular-weight distribution analysis.
Size Exclusion Chromatography (SEC)
A liquid-phase form of size-based separation used for macromolecules in aqueous or polar solvents, including biopolymers, polysaccharides, and water-soluble synthetic polymers.
Pore Size
The diameter of the pores in the stationary phase. Larger pores allow high-molecular-weight species to access the stationary phase, enabling accurate SEC/GPC characterization of large polymers.
Aqueous GPC Media
Polymer or silica-based stationary phases engineered for compatibility with water, buffers, and polar solvents. Used for hydrophilic polymers and biopolymers that cannot tolerate organic solvent systems.
Polar Gel Media (e.g., PolarGel)
Hydrophilic, solvent-resistant phases designed for reproducible separations in water, mixed aqueous systems, or high-salt environments—ideal for polymers that swell or degrade in organic-only conditions.
What types of samples can be analyzed using aqueous GPC/SEC columns?
Aqueous GPC/SEC columns are designed for polymers, biomolecules, polysaccharides, water-soluble plastics, and other macromolecules analyzed in water, buffers, or polar solvents. They offer reliable size-based separation for a wide range of hydrophilic materials.
What is the benefit of using PL aquagel-OH or PolarGel columns?
PL aquagel-OH and PolarGel columns provide excellent stability in aqueous and mixed solvent systems, low nonspecific adsorption, and highly reproducible molecular weight determinations—ideal for routine QC and advanced research applications.
Are these aqueous GPC/SEC columns compatible with standard HPLC systems?
Yes. These columns are compatible with conventional HPLC and GPC/SEC systems using aqueous mobile phases. Multiple dimensions, porosities, and hardware formats allow easy integration into existing workflows.
Product List
| SKU | Name | Type | Length | Inner Diameter (ID) | Particle Size |
|---|---|---|---|---|---|
SKU
PL1149-1840
|
Name
PL1149-1840 - PL aquagel-OH Guard 8um 50 x 7.5 mm
|
Type
Guard
|
Length
50 mm
|
Inner Diameter (ID)
7.5 mm
|
Particle Size
8 um
|
SKU
PL1149-1530
|
Name
PL1149-1530 - PL aquagel-OH Guard 5um 50 x 7.5 mm
|
Type
Guard
|
Length
50 mm
|
Inner Diameter (ID)
7.5 mm
|
Particle Size
5 um
|
SKU
PL1120-6830
|
Name
PL1120-6830 - PL aquagel-OH 30 8um 300 x 7.5 mm
|
Type
HPLC Column
|
Length
300 mm
|
Inner Diameter (ID)
7.5 mm
|
Particle Size
8 um
|
SKU
PL1249-6150
|
Name
PL1249-6150 - PL aquagel-OH 50 8um 300 x 25 mm
|
Type
HPLC Column
|
Length
300 mm
|
Inner Diameter (ID)
25 mm
|
Particle Size
8 um
|
SKU
PL1120-6520
|
Name
PL1120-6520 - PL aquagel-OH 20 5um 300 x 7.5 mm
|
Type
HPLC Column
|
Length
300 mm
|
Inner Diameter (ID)
7.5 mm
|
Particle Size
5 um
|
SKU
PL1249-6140
|
Name
PL1249-6140 - PL aquagel-OH 40 8um 300 x 25 mm
|
Type
HPLC Column
|
Length
300 mm
|
Inner Diameter (ID)
25 mm
|
Particle Size
8 um
|
SKU
PL1120-3830
|
Name
PL1120-3830 - PL Rapide Aqua L 150 x 7.5 mm
|
Type
HPLC Column
|
Length
150 mm
|
Inner Diameter (ID)
7.5 mm
|
Particle Size
3 um
|
SKU
PL1117-6830
|
Name
PL1117-6830 - Polargel-L 300 x 7.5 mm
|
Type
HPLC Column
|
Length
300 mm
|
Inner Diameter (ID)
7.5 mm
|
Particle Size
8 um
|
SKU
PL1249-6100
|
Name
PL1249-6100 - PL aquagel-OH MIXED-H 8um 300 x 25 mm
|
Type
HPLC Column
|
Length
300 mm
|
Inner Diameter (ID)
25 mm
|
Particle Size
8 um
|
SKU
PL1117-6800
|
Name
PL1117-6800 - Polargel-M 300 x 7.5 mm
|
Type
HPLC Column
|
Length
300 mm
|
Inner Diameter (ID)
7.5 mm
|
Particle Size
8 um
|
SKU
PL1249-1120
|
Name
PL1249-1120 - PL aquagel-OH Guard 25 x 25 mm
|
Type
Guard
|
Length
25 mm
|
Inner Diameter (ID)
25 mm
|
Particle Size
10 um
|
SKU
PL1117-1830
|
Name
PL1117-1830 - Polargel-L Guard 50 x 7.5 mm
|
Type
Guard
|
Length
50 mm
|
Inner Diameter (ID)
7.5 mm
|
Particle Size
8 um
|