QuEChERS Supplier

An acronym for Quick, Easy, Cheap, Effective, Rugged, and Safe, QuEChERS is a widely adopted sample preparation technique used primarily for multiresidue pesticide and contaminant analysis in food and environmental matrices.

Pre-filled centrifuge tubes containing measured salts and buffering agents that facilitate liquid–liquid partitioning of analytes from complex matrices prior to cleanup and instrumental analysis.

A cleanup technique in which sorbent materials are added directly to the extract to remove matrix interferences such as lipids, pigments, sugars, and organic acids prior to LC/MS or GC/MS analysis.

A QuEChERS buffering formulation aligned with AOAC Official Methods, typically using acetate buffering salts to maintain pH control during pesticide extraction.

A European Norm (EN 15662) QuEChERS buffering system using citrate salts to maintain controlled pH conditions and improve stability for base-sensitive pesticides.

Signal enhancement or suppression caused by co-extracted compounds in complex samples, which can impact quantitation accuracy in LC/MS and GC/MS workflows.

AOAC QuEChERS methods typically use acetate buffering salts, while EN (European Norm 15662) methods use citrate buffering systems. The EN method often provides improved stability for base-sensitive pesticides and is widely used in European regulatory workflows. Selection depends on the validated method your laboratory follows.

dSPE cleanup is used after extraction to remove matrix interferences such as lipids, pigments, sugars, and organic acids. It reduces matrix effects in LC/MS and GC/MS analysis and improves method robustness, particularly for complex food and agricultural samples.

Yes. Agilent QuEChERS extraction tubes and dispersive kits are validated for multiresidue workflows using LC/MS/MS and GC/MS/MS systems. Proper sorbent selection ensures reduced ion suppression and improved chromatographic performance.

Sorbent selection depends on the sample matrix. PSA removes organic acids and sugars, C18 targets lipids, GCB removes pigments, and specialty sorbents such as Z-Sep improve cleanup of fatty or complex samples. The correct combination should align with your validated regulatory method and matrix type.

Yes. While originally developed for fruits and vegetables, QuEChERS methods are widely adapted for grains, dairy, meat, environmental samples, and other complex matrices. Method adjustments and sorbent selection are critical to maintaining recovery and minimizing matrix effects.