Agilent HPLC Columns
ZORBAX, Poroshell, Polaris & Pursuit HPLC Columns
Chrom Tech supplies a complete portfolio of Agilent HPLC columns for small-molecule analysis, including superficially porous InfinityLab Poroshell 120 columns and fully porous ZORBAX, Polaris, and Pursuit series. Together, these families support an exceptionally wide range of separation modes, selectivity options, and analytical workflows.
Reversed-phase LC remains the dominant technique for small-molecule separations, and choosing the right phase is critical for achieving consistent retention, resolution, and peak shape. Agilent’s column platforms deliver industry-leading reproducibility and efficiency, with multiple bonded phases, pore sizes, and particle technologies engineered for both HPLC and UHPLC performance.
For expert guidance in selecting the ideal Agilent column for your application, contact Chrom Tech to connect with our chromatography specialists.
Agilent HPLC Column Categories
Explore genuine Agilent HPLC Columns
Shop InfinityLab Poroshell 120
Agilent Poroshell 120 Reversed Phase HPLC Columns
- Up to 50% less back pressure
- Superior column performance
- Narrow particle size distribution
- Three particle sizes (1.9, 2.7, 4µm)
- All-in-One Kits for Validation
Shop ZORBAX Eclipse Plus
The ultimate in performance for silica-based columns.
- Ideal column for method development
- High level of performance—peak shape, efficiency, resolution, and lifetime
- All sample types: acids, bases and neutrals
Shop ZORBAX Eclipse XDB
Four selectivity choices for method development optimization
- Good peak shape for basic, acidic and neutral compounds
- Wide pH range (2–9)
- Particle sizes from 1.8 to 7 µm
- Long lifetime with XDB and double endcapping
Shop ZORBAX 80Å StableBond
Provide exceptional low-pH stability, long lifetime, and broad selectivity across six bonded phases.
- Longest column lifetime
- Best reproducibility for low pH
- Use at high temperature & low pH without degradation
Shop ZORBAX 80Å Extend-C18
Deliver high efficiency, excellent peak shape, and long life at high pH (up to 11.5), with bidentate bonding ideal for LC/MS peptide analysis.
- Bidentate bonding and double endcapping
- Better peak shape than polymer-based compounds
- High sensitivity for separations of peptides
Shop ZORBAX Bonus-RP Columns
Provide excellent peak shape for challenging basic compounds, offering unique reversed-phase selectivity, high aqueous compatibility, and strong low-pH stability through embedded-polar bonding and steric protection.
- For low/mid pH basic compounds
- Unique reversed-phase selectivity
- Novel bonding technology
- Usable in 100% aqueous mobile phases
Shop ZORBAX Specialty Columns
For unique or complex separations not achievable with standard reversed-phase phases.
- Targeted selectivity for specialized or difficult separations
- Optimized chemistries beyond standard reversed-phase phases
- Reliable performance for unique method requirements
Shop Pursuit XRs Columns
Reliable performance across multiple particle sizes and phase chemistries.
- Multiple chemistries including USP L1, L7, and L11
- Traditional and high-carbon-load bonding options
- Wide range of dimensions, including preparative formats
Shop Polaris HPLC Columns
Deliver robust, aqueous-compatible performance for increasingly polar compounds.
- Designed for high-aqueous conditions
- Improved retention and peak shape
- Multiple C18 and C8 chemistries
Reversed-Phase Chromatography (RP)
The most widely used LC mode. Utilizes non-polar stationary phases such as C18 or C8 and polar mobile phases. Ideal for small molecules requiring predictable retention and high reproducibility.
Superficially Porous Particles (SPP)
Also called “core-shell” particles. Used in Agilent Poroshell 120 columns to deliver UHPLC-grade efficiency with reduced back-pressure, enabling faster and higher-resolution separations.
Fully Porous Particles (FPP)
Traditional particle design used in Agilent ZORBAX, Polaris, and Pursuit columns. Offers broad selectivity, robust durability, and compatibility across classic and modern LC methods.
Particle Size
A key factor influencing efficiency, pressure, and resolution. Smaller particles (≤2–3 µm) deliver UHPLC-level performance, while 3.5–5 µm particles are ideal for standard HPLC systems.
Stationary Phase
The bonded surface chemistry—such as C18, C8, Phenyl-Hexyl, CN, or Bonus-RP—that determines retention, selectivity, and overall chromatographic behavior.
What types of Agilent HPLC columns does Chrom Tech offer?
Chrom Tech offers the full Agilent portfolio, including InfinityLab Poroshell 120, ZORBAX Eclipse Plus and XDB, StableBond, Extend-C18, Bonus-RP, Polaris, and Pursuit XRs columns—optimized for small-molecule separations.
What is the difference between Poroshell and ZORBAX columns?
Poroshell 120 columns use superficially porous particles for higher efficiency and faster separations, while ZORBAX columns are fully porous and offer broad selectivity across many stationary phases and applications.
Can these Agilent columns be used for UHPLC?
Yes. Many Agilent columns—including Poroshell 120, ZORBAX Eclipse Plus, and Pursuit XRs—are rated for UHPLC platforms and deliver high efficiency and excellent resolution at elevated pressures.
Product List
| SKU | Name | LC Column Phase | Particle Size | Inner Diameter (ID) | Length |
|---|---|---|---|---|---|
SKU
693970-301K
|
Name
693970-301K - Agilent InfinityLab Poroshell 120 HILIC, 3.0 x 150 mm, 4 um, MVK 3/pk
|
LC Column Phase
HILIC
|
Particle Size
4 um
|
Inner Diameter (ID)
3 mm
|
Length
150 mm
|
SKU
693770-912K
|
Name
693770-912K - Agilent InfinityLab Poroshell 120 Phenyl-Hexyl x, 2.1 x 150 mm, 4 um, MVK 3/pk
|
LC Column Phase
Phenyl-Hexyl
|
Particle Size
4 um
|
Inner Diameter (ID)
2.1 mm
|
Length
150 mm
|
SKU
693770-906K
|
Name
693770-906K - Agilent InfinityLab Poroshell 120 EC-C8, 2.1 x 150 mm, 4 um, MVK 3/pk
|
LC Column Phase
EC-C8
|
Particle Size
4 um
|
Inner Diameter (ID)
2.1 mm
|
Length
150 mm
|
SKU
693770-902K
|
Name
693770-902K - Agilent InfinityLab Poroshell 120 EC-C18, 2.1 x 150 mm, 4 um, MVK 3/pk
|
LC Column Phase
EC-C18
|
Particle Size
4 um
|
Inner Diameter (ID)
2.1 mm
|
Length
150 mm
|
SKU
693770-901K
|
Name
693770-901K - Agilent InfinityLab Poroshell 120 HILIC, 2.1 x 150 mm, 4 um, MVK 3/pk
|
LC Column Phase
HILIC
|
Particle Size
4 um
|
Inner Diameter (ID)
2.1 mm
|
Length
150 mm
|
SKU
693770-408K
|
Name
693770-408K - Agilent InfinityLab Poroshell 120 PFP, 2.1 x 150 mm, 4 um, MVK 3/pk
|
LC Column Phase
PFP
|
Particle Size
4 um
|
Inner Diameter (ID)
2.1 mm
|
Length
150 mm
|
SKU
693575-302
|
Name
693575-302 - InfinityLab Poroshell 120 EC-C18, 3.0 x 150 mm, 2.7 um, 1000 bar
|
LC Column Phase
EC-C18
|
Particle Size
2.7 um
|
Inner Diameter (ID)
3 mm
|
Length
150 mm
|
SKU
690970-912K
|
Name
690970-912K - Agilent InfinityLab Poroshell 120 Phenyl-Hexyl, 4.6 x 250 mm, 4 um, MVK 3/pk
|
LC Column Phase
Phenyl-Hexyl
|
Particle Size
4 um
|
Inner Diameter (ID)
4.6 mm
|
Length
250 mm
|
SKU
690970-906K
|
Name
690970-906K - Agilent InfinityLab Poroshell 120 EC-C8, 4.6 x 250 mm, 4 um, MVK 3/pk
|
LC Column Phase
EC-C8
|
Particle Size
4 um
|
Inner Diameter (ID)
4.6 mm
|
Length
250 mm
|
SKU
690970-902K
|
Name
690970-902K - Agilent InfinityLab Poroshell 120 EC-C18, 4.6 x 250 mm, 4 um, MVK 3/pk
|
LC Column Phase
EC-C18
|
Particle Size
4 um
|
Inner Diameter (ID)
4.6 mm
|
Length
250 mm
|
SKU
690970-901K
|
Name
690970-901K - Agilent InfinityLab Poroshell 120 HILIC, 4.6 x 250 mm, 4 um, MVK 3/pk
|
LC Column Phase
HILIC
|
Particle Size
4 um
|
Inner Diameter (ID)
4.6 mm
|
Length
250 mm
|
SKU
690970-408K
|
Name
690970-408K - Agilent InfinityLab Poroshell 120 PFP, 4.6 x 250 mm, 4 um, MVK 3/pk
|
LC Column Phase
PFP
|
Particle Size
4 um
|
Inner Diameter (ID)
4.6 mm
|
Length
250 mm
|