Agilent HPLC Columns
ZORBAX, Poroshell, Polaris & Pursuit HPLC Columns
Chrom Tech supplies a complete portfolio of Agilent HPLC columns for small-molecule analysis, including superficially porous InfinityLab Poroshell 120 columns and fully porous ZORBAX, Polaris, and Pursuit series. Together, these families support an exceptionally wide range of separation modes, selectivity options, and analytical workflows.
Reversed-phase LC remains the dominant technique for small-molecule separations, and choosing the right phase is critical for achieving consistent retention, resolution, and peak shape. Agilent’s column platforms deliver industry-leading reproducibility and efficiency, with multiple bonded phases, pore sizes, and particle technologies engineered for both HPLC and UHPLC performance.
For expert guidance in selecting the ideal Agilent column for your application, contact Chrom Tech to connect with our chromatography specialists.
Agilent HPLC Column Categories
Explore genuine Agilent HPLC Columns
Reversed-Phase Chromatography (RP)
The most widely used LC mode. Utilizes non-polar stationary phases such as C18 or C8 and polar mobile phases. Ideal for small molecules requiring predictable retention and high reproducibility.
Superficially Porous Particles (SPP)
Also called “core-shell” particles. Used in Agilent Poroshell 120 columns to deliver UHPLC-grade efficiency with reduced back-pressure, enabling faster and higher-resolution separations.
Fully Porous Particles (FPP)
Traditional particle design used in Agilent ZORBAX, Polaris, and Pursuit columns. Offers broad selectivity, robust durability, and compatibility across classic and modern LC methods.
Particle Size
A key factor influencing efficiency, pressure, and resolution. Smaller particles (≤2–3 µm) deliver UHPLC-level performance, while 3.5–5 µm particles are ideal for standard HPLC systems.
Stationary Phase
The bonded surface chemistry—such as C18, C8, Phenyl-Hexyl, CN, or Bonus-RP—that determines retention, selectivity, and overall chromatographic behavior.
What types of Agilent HPLC columns does Chrom Tech offer?
Chrom Tech offers the full Agilent portfolio, including InfinityLab Poroshell 120, ZORBAX Eclipse Plus and XDB, StableBond, Extend-C18, Bonus-RP, Polaris, and Pursuit XRs columns—optimized for small-molecule separations.
What is the difference between Poroshell and ZORBAX columns?
Poroshell 120 columns use superficially porous particles for higher efficiency and faster separations, while ZORBAX columns are fully porous and offer broad selectivity across many stationary phases and applications.
Can these Agilent columns be used for UHPLC?
Yes. Many Agilent columns—including Poroshell 120, ZORBAX Eclipse Plus, and Pursuit XRs—are rated for UHPLC platforms and deliver high efficiency and excellent resolution at elevated pressures.
Product List
| SKU | Name | LC Column Phase | Particle Size | Inner Diameter (ID) | Length |
|---|---|---|---|---|---|
SKU
650750-408
|
Name
650750-408 - Poroshell 120 PFP, 2.1 x 250 mm, 4um
|
LC Column Phase
PFP
|
Particle Size
4 um
|
Inner Diameter (ID)
2.1 mm
|
Length
250 mm
|
SKU
5185-5923
|
Name
5185-5923 - Extend Guard, 1.0x17mm, 5um, 3/pk
|
LC Column Phase
Extend-C18
|
Particle Size
5 um
|
Inner Diameter (ID)
1 mm
|
Length
17 mm
|
SKU
5185-5922
|
Name
5185-5922 - Bonus-RP Guard, 1.0x17mm, 5um
|
LC Column Phase
Bonus-RP
|
Particle Size
5 um
|
Inner Diameter (ID)
1 mm
|
Length
17 mm
|
SKU
5185-5921
|
Name
5185-5921 - Eclipse XDB Guard, 1.0x17mm, 5um
|
LC Column Phase
Eclipse XDB-C18
|
Particle Size
5 um
|
Inner Diameter (ID)
1 mm
|
Length
17 mm
|
SKU
5185-5920
|
Name
5185-5920 - StableBond Guard, 1.0x17mm, 5um, 3/pk
|
LC Column Phase
SB-C18
|
Particle Size
5 um
|
Inner Diameter (ID)
1 mm
|
Length
17 mm
|
SKU
5064-8253
|
Name
5064-8253 - ZORBAX SB C18 5u guard 35 x 0.3mm
|
LC Column Phase
SB-C18
|
Particle Size
5 um
|
Inner Diameter (ID)
0.3 mm
|
Length
35 mm
|
SKU
5064-8298
|
Name
5064-8298 - ZORBAX XDB C18 RR 3.5u 35 x 0.5mm
|
LC Column Phase
Eclipse XDB-C18
|
Particle Size
3.5 um
|
Inner Diameter (ID)
0.5 mm
|
Length
35 mm
|
SKU
5064-8288
|
Name
5064-8288 - ZORBAX XDB C18 RR 3.5u 150 x 0.5mm
|
LC Column Phase
Eclipse XDB-C18
|
Particle Size
3.5 um
|
Inner Diameter (ID)
0.5 mm
|
Length
150 mm
|
SKU
5064-8262
|
Name
5064-8262 - ZORBAX SB C18 RR 3.5 u 150 x 0.5mm
|
LC Column Phase
SB-C18
|
Particle Size
3.5 um
|
Inner Diameter (ID)
0.5 mm
|
Length
150 mm
|
SKU
5064-8261
|
Name
5064-8261 - ZORBAX SB C18 RR 3.5u 150 x 0.3 mm
|
LC Column Phase
SB-C18
|
Particle Size
3.5 um
|
Inner Diameter (ID)
0.3 mm
|
Length
150 mm
|
SKU
5064-8260
|
Name
5064-8260 - ZORBAX SB C18 RR 3.5u, 35 x 0.5 mm
|
LC Column Phase
SB-C18
|
Particle Size
3.5 um
|
Inner Diameter (ID)
0.5 mm
|
Length
35 mm
|
SKU
5064-8256
|
Name
5064-8256 - ZORBAX SB C18 5u 150 x 0.5mm
|
LC Column Phase
SB-C18
|
Particle Size
5 um
|
Inner Diameter (ID)
0.5 mm
|
Length
150 mm
|