Agilent HPLC Columns

ZORBAX, Poroshell, Polaris & Pursuit HPLC Columns

Chrom Tech supplies a complete portfolio of Agilent HPLC columns for small-molecule analysis, including superficially porous InfinityLab Poroshell 120 columns and fully porous ZORBAX, Polaris, and Pursuit series. Together, these families support an exceptionally wide range of separation modes, selectivity options, and analytical workflows.

Reversed-phase LC remains the dominant technique for small-molecule separations, and choosing the right phase is critical for achieving consistent retention, resolution, and peak shape. Agilent’s column platforms deliver industry-leading reproducibility and efficiency, with multiple bonded phases, pore sizes, and particle technologies engineered for both HPLC and UHPLC performance.

For expert guidance in selecting the ideal Agilent column for your application, contact Chrom Tech to connect with our chromatography specialists.

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Key Definitions ▸
Reversed-Phase Chromatography (RP)
The most widely used LC mode. Utilizes non-polar stationary phases such as C18 or C8 and polar mobile phases. Ideal for small molecules requiring predictable retention and high reproducibility.
Superficially Porous Particles (SPP)
Also called “core-shell” particles. Used in Agilent Poroshell 120 columns to deliver UHPLC-grade efficiency with reduced back-pressure, enabling faster and higher-resolution separations.
Fully Porous Particles (FPP)
Traditional particle design used in Agilent ZORBAX, Polaris, and Pursuit columns. Offers broad selectivity, robust durability, and compatibility across classic and modern LC methods.
Particle Size
A key factor influencing efficiency, pressure, and resolution. Smaller particles (≤2–3 µm) deliver UHPLC-level performance, while 3.5–5 µm particles are ideal for standard HPLC systems.
Stationary Phase
The bonded surface chemistry—such as C18, C8, Phenyl-Hexyl, CN, or Bonus-RP—that determines retention, selectivity, and overall chromatographic behavior.
Frequently Asked Questions ▸
What types of Agilent HPLC columns does Chrom Tech offer?
Chrom Tech offers the full Agilent portfolio, including InfinityLab Poroshell 120, ZORBAX Eclipse Plus and XDB, StableBond, Extend-C18, Bonus-RP, Polaris, and Pursuit XRs columns—optimized for small-molecule separations.
What is the difference between Poroshell and ZORBAX columns?
Poroshell 120 columns use superficially porous particles for higher efficiency and faster separations, while ZORBAX columns are fully porous and offer broad selectivity across many stationary phases and applications.
Can these Agilent columns be used for UHPLC?
Yes. Many Agilent columns—including Poroshell 120, ZORBAX Eclipse Plus, and Pursuit XRs—are rated for UHPLC platforms and deliver high efficiency and excellent resolution at elevated pressures.

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SKU Name LC Column Phase Particle Size Inner Diameter (ID) Length
SKU
770100-902
Name
770100-902 - PrepHT,Zorbax,Extend,21.2x100mm,5uCrt
LC Column Phase
Extend-C18
Particle Size
5 um
Inner Diameter (ID)
21.2 mm
Length
100 mm
SKU
773450-302
Name
773450-302 - Extend-C18 3.0x150mm 5u
LC Column Phase
Extend-C18
Particle Size
5 um
Inner Diameter (ID)
3 mm
Length
150 mm
SKU
770050-902
Name
770050-902 - PrepHT,Zorbax,Extend,21.2x50mm,5uCrt
LC Column Phase
Extend-C18
Particle Size
5 um
Inner Diameter (ID)
21.2 mm
Length
50 mm
SKU
763953-902
Name
763953-902 - Extend-C18 3.5u 4.6x150mm
LC Column Phase
Extend-C18
Particle Size
3.5 um
Inner Diameter (ID)
4.6 mm
Length
150 mm
SKU
766953-902
Name
766953-902 - Extend-C18 3.5u 4.6x75mm
LC Column Phase
Extend-C18
Particle Size
3.5 um
Inner Diameter (ID)
4.6 mm
Length
75 mm
SKU
763600-902
Name
763600-902 - Extend-C18, 1 x 150 mm, 3.5 micron
LC Column Phase
Extend-C18
Particle Size
3.5 um
Inner Diameter (ID)
1 mm
Length
150 mm
SKU
757700-902
Name
757700-902 - RRHD Extend-C18,2.1x50mm,1.8um,1200bar
LC Column Phase
Extend-C18
Particle Size
1.8 um
Inner Diameter (ID)
2.1 mm
Length
50 mm
SKU
761753-902
Name
761753-902 - Extend-C18, 2.1x100mm 3.5um
LC Column Phase
Extend-C18
Particle Size
3.5 um
Inner Diameter (ID)
2.1 mm
Length
100 mm
SKU
757700-302
Name
757700-302 - RRHD Extend-C18,3.0x50mm,1.8um,1200bar
LC Column Phase
Extend-C18
Particle Size
1.8 um
Inner Diameter (ID)
3 mm
Length
50 mm
SKU
760450-902
Name
760450-902 - Extend-C18, LC/MS Column, 5u, 2.1x50mm
LC Column Phase
Extend-C18
Particle Size
5 um
Inner Diameter (ID)
2.1 mm
Length
50 mm
SKU
765600-902
Name
765600-902 - Extend-C18, 1 x 50 mm, 3.5 um
LC Column Phase
Extend-C18
Particle Size
3.5 um
Inner Diameter (ID)
1 mm
Length
50 mm
SKU
735954-302
Name
735954-302 - Extend-C18, 3.0x50mm 3.5um
LC Column Phase
Extend-C18
Particle Size
3.5 um
Inner Diameter (ID)
3 mm
Length
50 mm