ZORBAX Eclipse Plus
Agilent ZORBAX Eclipse Plus HPLC Columns
The Agilent ZORBAX Eclipse Plus family delivers industry-leading performance for silica-based HPLC columns, offering exceptional peak shape, high efficiency, and reliable resolution across acids, bases, and neutral compounds. Designed with Agilent’s advanced silica and bonding technology, these columns minimize silanol interactions to produce clean, symmetrical peaks—especially for challenging basic analytes.
- Universal selectivity that supports fast, confident method development across diverse compound classes.
- Outstanding peak shape for basic analytes, delivering sharper resolution and improved quantitation.
Eclipse Plus columns are the recommended first choice for method development thanks to their consistent performance and broad applicability. Choose 1.8 µm Rapid Resolution columns for maximum speed and high-throughput workflows, or select 3.5 µm and 5 µm options for robust, easily transferable standard-pressure methods. Across all particle sizes, Eclipse Plus supports simple, reliable method transfer and long column lifetime.
Silica-Based Column
A column packed with high-purity silica particles. Known for excellent efficiency, strong mechanical strength, and broad applicability across reversed-phase HPLC methods.
Peak Shape
A measure of chromatographic performance that reflects symmetry, efficiency, and interaction between analytes and the stationary phase. Improved peak shape enhances resolution and quantitation accuracy.
Bonded Phase
The chemically attached functional layer (e.g., C18, phenyl) on the silica surface that governs retention and selectivity. Eclipse Plus columns use highly controlled, proprietary bonding for enhanced reproducibility.
Particle Size
A key determinant of resolution, backpressure, and speed. Eclipse Plus columns are available in 1.8 µm, 3.5 µm, and 5 µm for easy method transfer and flexible system compatibility.
Method Development Column
A column offering broad selectivity, stable performance, and robust peak shape—ideal for rapidly screening conditions and building reliable HPLC methods across diverse analytes.
What makes ZORBAX Eclipse Plus ideal for method development?
Eclipse Plus columns deliver exceptional peak shape for acids, bases, and neutrals, making them a universally strong first choice. Their optimized silica and bonding technologies ensure predictable retention and reliable method transfer.
Which particle size should I use for my application?
Choose 1.8 µm for fast, high-resolution UHPLC separations, 3.5 µm for Rapid Resolution HPLC, and 5 µm for conventional LC methods. All sizes offer straightforward method transfer.
Are Eclipse Plus columns good for challenging basic compounds?
Yes. Eclipse Plus columns are specifically designed to deliver sharp, symmetrical peaks for strong bases—often outperforming standard C18 or C8 columns in basic compound analysis.
Are these columns compatible with standard LC systems?
Yes. Eclipse Plus columns are available in formats suitable for UHPLC, RRLC, and traditional HPLC platforms, making them adaptable to any workflow.
Product List
| SKU | Name | LC Column Phase | Particle Size | Inner Diameter (ID) | Length |
|---|---|---|---|---|---|
SKU
959757-306
|
Name
959757-306 - RRHD Eclipse Plus C8, 3.0x50mm, 1.8um
|
LC Column Phase
Eclipse Plus C8
|
Particle Size
1.8 um
|
Inner Diameter (ID)
3 mm
|
Length
50 mm
|
SKU
959757-302
|
Name
959757-302 - RRHD Eclipse Plus C18, 3.0x50mm, 1.8um
|
LC Column Phase
Eclipse Plus C18
|
Particle Size
1.8 um
|
Inner Diameter (ID)
3 mm
|
Length
50 mm
|
SKU
823750-901
|
Name
823750-901 - UHPLC Grd, Ecl. Plus C 18,3.0mm, 1.8um,3pk
|
LC Column Phase
Eclipse Plus C18
|
Particle Size
1.8 um
|
Inner Diameter (ID)
3 mm
|
Length
5 mm
|
SKU
959963-906
|
Name
959963-906 - Eclipse Plus C8, 4.6x150mm,3.5um
|
LC Column Phase
Eclipse Plus C8
|
Particle Size
3.5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
150 mm
|
SKU
959963-902
|
Name
959963-902 - Eclipse Plus C18,4.6 x 150mm, 3.5um
|
LC Column Phase
Eclipse Plus C18
|
Particle Size
3.5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
150 mm
|
SKU
959963-312
|
Name
959963-312 - Eclipse Plus Phenyl-Hexyl,3x150mm,3.5um
|
LC Column Phase
Eclipse Plus Phenyl-Hexyl
|
Particle Size
3.5 um
|
Inner Diameter (ID)
3 mm
|
Length
150 mm
|
SKU
959963-306
|
Name
959963-306 - Eclipse Plus C8, 3.0x150mm,3.5um
|
LC Column Phase
Eclipse Plus C8
|
Particle Size
3.5 um
|
Inner Diameter (ID)
3 mm
|
Length
150 mm
|
SKU
959963-302
|
Name
959963-302 - Eclipse Plus C18,3.0 x 150mm, 3.5um
|
LC Column Phase
Eclipse Plus C18
|
Particle Size
3.5 um
|
Inner Diameter (ID)
3 mm
|
Length
150 mm
|
SKU
959961-912
|
Name
959961-912 - Eclipse Plus Phenyl-Hexyl,4.6x100mm,3.5u
|
LC Column Phase
Eclipse Plus Phenyl-Hexyl
|
Particle Size
3.5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
100 mm
|
SKU
959961-906
|
Name
959961-906 - Eclipse Plus C8, 4.6x100mm,3.5um
|
LC Column Phase
Eclipse Plus C8
|
Particle Size
3.5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
100 mm
|
SKU
959759-906
|
Name
959759-906 - RRHD Eclipse Plus C8, 2.1x150mm, 1.8um
|
LC Column Phase
Eclipse Plus C8
|
Particle Size
1.8 um
|
Inner Diameter (ID)
2.1 mm
|
Length
150 mm
|
SKU
959961-902
|
Name
959961-902 - Eclipse Plus C18,4.6 x 100mm, 3.5um
|
LC Column Phase
Eclipse Plus C18
|
Particle Size
3.5 um
|
Inner Diameter (ID)
4.6 mm
|
Length
100 mm
|