Semivolatile

Semivolatile column

Agilent Semivolatile GC Columns

Agilent Semivolatile GC columns are engineered to deliver highly reliable, low-bleed performance for the separation of complex semivolatile organic compounds (SVOCs) in environmental, industrial, and regulatory testing workflows. These columns provide the inertness, thermal stability, and selectivity required to accurately analyze diverse compound classes such as PAHs, phenols, phthalates, pesticides, nitrosamines, and dioxins, even in demanding matrices. Designed for consistency, robustness, and maximum sensitivity, Agilent’s semivolatile solutions ensure dependable quantitation at trace levels for compliance-driven methods.

Chrom Tech, as an authorized distributor of Agilent GC columns, offers three specialized column families tailored for semivolatile analysis. The DB-UI 8270D column features advanced Ultra Inert deactivation and is optimized for EPA Method 8270D, delivering excellent peak shapes and reduced breakdown for active or high-boiling analytes. The DB-5.625 column provides balanced selectivity for halogenated and non-halogenated semivolatiles, making it ideal for combined analyses that require strong resolution of multiple compound classes. For highly toxic and tightly regulated dioxins and furans, the DB-Dioxin column offers exceptional selectivity and extremely low bleed, supporting the precision and sensitivity demanded by global dioxin monitoring programs.

Together, Agilent DB-UI 8270D, DB-5.625, and DB-Dioxin GC columns form a robust portfolio for laboratories performing semivolatile organic compound analysis under EPA, international, and industry-specific regulatory frameworks. These columns provide rugged, dependable performance that ensures accurate identification, improved laboratory efficiency, and long-term analytical confidence.
Key Definitions â–¸
DB-UI 8270D
An Ultra Inert GC column engineered for EPA Method 8270D semivolatile analysis. DB-UI 8270D provides extremely low activity and improved thermal stability, ensuring better recovery, peak symmetry, and reduced breakdown for PAHs, phenols, nitrosamines, and other active semivolatile analytes.
DB-5.625
A proprietary mid-polarity GC column designed to provide balanced selectivity for halogenated and non-halogenated semivolatile compounds. DB-5.625 is commonly used in environmental and industrial testing where multiple compound classes must be analyzed in a single run.
DB-Dioxin
A highly specialized GC column offering exceptional selectivity and ultra-low bleed for dioxins and furans. DB-Dioxin is used for global regulatory monitoring programs requiring precise identification and quantitation of trace-level toxic compounds.
Semivolatile Organic Compounds (SVOCs)
A broad class of organic chemicals with lower volatility than VOCs and higher boiling points, including PAHs, phenols, phthalates, nitrosamines, pesticides, and dioxins. Their chemical diversity requires specialized GC column selectivity and strong thermal stability for accurate analysis.
Frequently Asked Questions â–¸
What types of compounds are best analyzed using Agilent semivolatile GC columns?
Agilent semivolatile GC columns are ideal for analyzing PAHs, phthalates, phenols, nitrosamines, pesticides, dioxins, and other medium- to high-boiling organic compounds. Their inertness and thermal stability make them well suited for EPA, environmental, and industrial testing workflows.
How do DB-UI 8270D, DB-5.625, and DB-Dioxin differ?
DB-UI 8270D is optimized for EPA Method 8270D and provides advanced Ultra Inert performance for active and high-boiling SVOCs.

DB-5.625 offers balanced selectivity for halogenated and non-halogenated semivolatiles, making it ideal for broad-scope environmental analyses.

DB-Dioxin is engineered for exceptional selectivity and ultra-low bleed necessary for trace-level dioxin and furan monitoring under stringent global regulations.
Why is low bleed important for semivolatile GC analysis?
Low bleed is essential for achieving stable baselines, maximizing MS sensitivity, and preventing interference with trace-level semivolatiles. Columns such as DB-UI 8270D and DB-Dioxin are specifically designed to minimize bleed, ensuring high accuracy in compliance-driven workflows.