Large Bore Fittings

Large Bore Fittings

IDEX Large Bore Fluidic Connections are engineered for reliable, low-restriction fluid transfer in laboratory and industrial workflows that require higher flow rates or larger tubing diameters. Featuring durable 5/16-24 and 1/2-20 threaded fittings, these components provide secure connections for a wide range of tubing sizes while maintaining excellent chemical compatibility and leak resistance.

  • Available with 5/16-24 or 1/2-20 threads
  • Compatible with 1/16", 1/8", 3/16", 1/4", 5/16", 3.0 mm, and 4.0 mm OD tubing

Commonly used in preparative chromatography, sample transfer, reagent delivery, and bulk fluid handling systems, IDEX large bore fittings, adapters, and connectors support efficient flow paths with minimal dead volume. Precision-machined from high-performance materials, these connections help maintain system integrity under demanding laboratory conditions.

Chrom Tech offers a broad selection of IDEX large bore fluidic components, with many popular configurations in stock and ready to ship—making it easy to build or upgrade your fluidic setup with confidence.

PART NO DESCRIPTION PORT PRESSURE RATING HEAD STYLE MATERIAL
  
LARGE BORE FITTINGS
XP-130Flangeless Fitting for 1/8" OD Tubing5/16-24 Flat-Bottom500 PSI (34 bar)Standard KnurlPEEK Natural/ETFE Yellow
XP-132Flangeless Fitting for 3/16" OD Tubing5/16-24 Flat-Bottom500 PSI (34 bar)Standard KnurlPEEK Natural/ETFE Blue
XP-137Super Flangeless Fitting for 3/16" OD Tubing5/16-24 Flat-Bottom500 PSI (34 bar)Standard KnurlPEEK Black/ETFE Green/SST
XP-141Super Flangeless Fitting for 1/16" OD Tubing5/16-24 Flat-Bottom1,350 PSI (93 bar)Standard KnurlPEEK Natural/ETFE Green/SST
XU-655Flangeless Fitting for 1/4" OD Tubing1/2-20 Flat-Bottom250 PSI (17 bar)Large KnurlPEEK Black/ETFE Natural
XU-662Flangeless Fitting for 5/16" OD Tubing1/2-20 Flat-Bottom250 PSI (17 bar)Large KnurlPEEK Black/ETFE Natural
REPLACEMENT FERRULES
P-133Flangeless Ferrule for 3/16" OD Tubing5/16-24 Flat-Bottom500 PSI (34 bar)—ETFE Blue
P-133NFlangeless Ferrule for 3/16" OD Tubing5/16-24 Flat-Bottom500 PSI (34 bar)—ETFE Natural
P-140Super Flangeless Ferrule for 3/16" OD Tubing5/16-24 Flat-Bottom500 PSI (34 bar)—ETFE Green
U-650Flangeless Ferrule for 1/4" OD Tubing1/2-20 Flat-Bottom250 PSI (17 bar)—ETFE Natural
U-660Flangeless Ferrule for 5/16" OD Tubing1/2-20 Flat-Bottom250 PSI (17 bar)—ETFE Natural
Key Definitions ▸
Large Bore Fluidic Connections
Fluid handling fittings and adapters designed for larger tubing diameters and higher flow rates, commonly used in preparative chromatography, reagent delivery, and bulk sample transfer systems.
5/16-24 and 1/2-20 Threads
Standard large-format thread sizes used to create secure, leak-resistant connections between tubing and ports in higher-flow laboratory fluidic assemblies.
Outer Diameter (OD)
The external measurement of tubing used to determine fitting compatibility. IDEX large bore connections support tubing sizes from 1/16" through 5/16", as well as 3.0 mm and 4.0 mm metric tubing.
Low Dead Volume
A design feature that minimizes trapped fluid within a connection, helping maintain consistent flow paths, reduce carryover, and improve analytical accuracy.
Preparative Chromatography
A chromatography technique focused on isolating larger quantities of compounds, requiring higher flow rates and larger bore fluidic components to support efficient separations.
Frequently Asked Questions ▸
What are IDEX large bore fluidic connections used for?
IDEX large bore connections are used when you need higher flow rates or larger tubing IDs for applications like preparative chromatography, bulk sample transfer, reagent delivery, and general higher-volume fluid handling where standard small-bore fittings may be too restrictive.
What thread sizes are considered “large bore” in this category?
This category focuses on fittings and ports that use 5/16-24 or 1/2-20 threads—common large-format standards used to support higher-flow fluidic connections.
Which tubing sizes are compatible with IDEX large bore connections?
IDEX large bore connections in this family are commonly used with 1/16", 1/8", 3/16", 1/4", 5/16" OD tubing, plus 3.0 mm and 4.0 mm metric OD tubing (compatibility depends on the specific fitting and ferrule set).
Do I need special ferrules or sleeves for large bore fittings?
Often, yes. Large bore connections typically require ferrules and/or sleeves matched to both the thread type (5/16-24 or 1/2-20) and the tubing OD/material. Using the correct ferrule set helps ensure a reliable seal and protects tubing from deformation or slippage.
How do I choose between 5/16-24 and 1/2-20?
Start with the thread size of the receiving port or device you are connecting to. Then select the fitting style that matches your tubing OD and desired flow path. If you are transitioning between standards, a thread adapter can help maintain a secure, leak-resistant interface.
What does “low dead volume” mean and why does it matter?
Low dead volume means the connection minimizes spaces where fluid can pool. This helps reduce carryover, improves response consistency, and supports cleaner transitions during sample transfer—especially important when switching solvents, fractions, or reagents.