Chromatography Knowledge Center
Explore Chromatography Guides, Compatibility Tools, and Technical Insights
Browse educational resources covering HPLC, GC, LC/MS, autosampler vials, fittings, and sample preparation workflows
The Chrom Tech Knowledge Center is a practical reference library for chromatography laboratories—built to help you select the right consumables, understand instrument compatibility, and troubleshoot analytical workflows across LC, GC, and sample preparation.
Use the topic sections below to explore technical guidance for autosampler vials, microplates, chromatography columns, sample preparation, and instrument accessories.
- Instrument compatibility
- Vial selection
- Closure selection
- Septa selection
- Plate uses
- Selection guidance
- Glass vs polypropylene
- Sealing methods
- Column care
- Peak resolution
- Guard vs inline filters
- Poroshell methods
- Fittings and unions
- Tubing selection
- Leak troubleshooting
- Dead volume and flow path
Autosampler Vials
Use these guides to match vial dimensions, thread types, and closure systems to your autosampler platform and method needs.
- How to Choose Autosampler Vials for HPLC & GC
- What’s the Difference Between a 1.5 mL and 2.0 mL Autosampler Vial?
- Glass, Plastic & Amber Vials: Which Is Best?
- How to Choose the Right Autosampler Vial Closure for Chromatography
- When Should You Use Vial Inserts in Autosampler Vials?
- How to Choose Storage Vials: Threading, F217 Liners & Seal Integrity
- Autosampler Vial Septa: How to Choose for Solvent Compatibility
- When to Use High Recovery Vials in Chromatography
- Prevent Sample Adsorption: Choosing Silanized or Premium Glass Vials
- Autosampler Vial Compatibility Guide – Waters, Agilent, Shimadzu, Thermo
- What Vials are Compatible with Agilent Technologies GC Autosamplers
- What Vials are Compatible with Agilent Technologies LC Autosamplers
- What Vials are Compatible with Thermo LC Autosamplers
- What Vials are Compatible with Waters Corporation Autosamplers
96-Well Plates
Explore practical guidance on 96-well plate formats, plate materials, well geometry, sealing methods, automation compatibility, and LC-MS sample preparation workflows.
- What Are 96-Well Plates Used For in LC-MS and Sample Prep?
- 96-Well Plate Selection Guide for LC-MS Workflows
- 96-Well Plate Bottom Types: Flat, U, V, and Pyramid
- Vials vs 96-Well Plates for LC-MS Sample Preparation
- Polypropylene vs Glass 96-Well Plates Explained
- Why Use 96-Well Plates with Glass Inserts for LCMS and Chromatography
- How to Maximize Sample Recovery in 96-Well Plates
- 96-Well Plate Automation Guide
- 96-Well vs 384-Well Plates: Key Differences Explained
- 96-Well Plate Sealing Methods: Films, Foils, and Cap Mats
- 96-Well Plate Dimensions: ANSI/SBS Standards Explained
LC Columns
Explore practical guidance on HPLC and UHPLC column care, pressure control, particle and pore size selection, guard column use, and Poroshell method optimization.
- HPLC Column Care and Maintenance Guide
- How Many Injections Can an HPLC Column Last?
- How to Extend HPLC Column Lifetime
- How Column Temperature Affects HPLC Resolution
- HPLC Column Pore Size vs Particle Size Explained
- How to Improve HPLC Peak Resolution
- How to Regenerate a C18 HPLC Column
- What Is End-Capping in HPLC Columns?
- What Is a Guard Column in HPLC?
- Inline Filter vs Guard Column for HPLC
- How to Reduce HPLC Column Backpressure
- Optimizing HPLC Methods with Poroshell Columns
- Method Transfer Between Poroshell and ZORBAX HPLC Columns
LC Accessories
Explore practical guidance on HPLC fittings, tubing, filters, valves, dead volume, backpressure, leaks, and full flow path optimization for LC and UHPLC systems.
- Inline Filter vs Guard Column for HPLC
- How to Cut HPLC Tubing Properly
- How to Properly Swage HPLC Fittings
- HPLC Fittings Guide: Types and Applications
- HPLC Union vs Adapter: What’s the Difference?
- Capillary Tubing Selection Guide for Agilent HPLC
- HPLC Tubing Selection Guide
- HPLC Dead Volume Explained
- How to Fix HPLC Leaks in Fittings and Connections
- Inline Filter vs Precolumn Filter in HPLC
- HPLC Valves Explained: Types and Applications
- How Accessories Affect HPLC Backpressure
- HPLC Flow Path Diagram Explained
There are no products listed under this category.