Inlet Septa

Inlet Septa for Gas Chromatography

Agilent inlet septa for gas chromatography (GC) are engineered to deliver clean, leak-free sealing and low-bleed performance, even under demanding high-temperature conditions. Advanced Green septa minimize sticking and coring, reducing contamination of the inlet liner and extending maintenance intervals.

Bleed Temperature Optimized (BTO) septa are preconditioned and ready to use with low-bleed, MS-compatible capillary columns, while long-life formulations are shaped for extended use and fewer changeouts. Explore Agilent’s complete portfolio of GC inlet septa to keep your instruments operating at peak performance with consistent, reproducible results.


Agilent Inlet Septa for Agilent GC Systems

Diameter Qty Non-Stick BTO Non-Stick Long Life Non-Stick Advanced Green Economical General Purpose
11 mm 50/pk 5183-4757 5183-4761 5183-4759 5080-8896-50
11 mm 100/pk 5183-4757-100 5183-4761-100 5183-4759-100 5080-8894-100
11 mm 400/pk 5190-3157 — 5190-3158 —

Agilent CrossLab Inlet Septa for Other GC Systems

Diameter Qty Non-Stick BTO Non-Stick Long Life Non-Stick Advanced Green Economical General Purpose
17 mm 24/pk 8010-0229 8010-0245 8010-0213 8010-0261
17 mm 48/pk 8010-0230 8010-0246 8010-0214 8010-0262
for Shimadzu 50/pk 8010-0231 — 8010-0215 8010-0263
for Shimadzu 100/pk 8010-0232 — 8010-0216 —

Summary of Premium Inlet Septa Characteristics

Characteristic BTO Long Life Advanced Green General Purpose
Bleed ✓✓✓ ✓ ✓✓
Lifetime ✓ ✓✓✓ ✓✓
Temperature Limit to 400 °C to 350 °C to 350 °C to 350 °C

Key Definitions â–¸
Bleed Temperature Optimized (BTO) Septa
Preconditioned, low-bleed septa designed for high-temperature and GC/MS workflows. Provide stable backgrounds up to 400 Â°C and reduce chemical noise for sensitive analyses.
Advanced Green Septa
High-performance non-stick septa that resist needle coring and sticking, helping prevent particulate contamination of inlet liners while maintaining durable, reliable sealing.
Long-Life Septa
Robust septa engineered for extended high-throughput operation, minimizing downtime by maintaining sealing performance through repeated injections and thermal cycles.
General Purpose Septa
Economical septa designed for routine GC workflows and moderate temperature operation. Suitable for laboratories prioritizing cost efficiency in standard applications.
Coring
The formation of septum fragments caused by the autosampler needle, which can enter the inlet, contaminate liners, and reduce chromatographic performance if not properly controlled.
Frequently Asked Questions â–¸
Why should I choose BTO septa for GC/MS applications?
BTO septa are preconditioned for extremely low bleed, minimizing background noise and improving detection limits in GC/MS workflows—especially at higher inlet temperatures.
What causes septa to fail or leak during operation?
Septa failure is typically caused by excessive temperature cycling, repeated needle penetrations, needle misalignment, or poor septum nut tension—all of which can compromise sealing integrity.
How often should inlet septa be replaced?
Replacement frequency depends on injection load, temperature, and septa type. Long-Life and Advanced Green septa last significantly longer, while standard septa may require more frequent replacement.
Are all Agilent septa compatible with every GC inlet?
No. Septa differ in diameter, shape, and performance characteristics. Always match the septum type to your instrument model and inlet configuration (e.g., S/SL, MMI, PTV, HS).