HPLC Vials & Closures

Screw Thread
9 mm screw thread HPLC vial
9 mm Wide Mouth
Autosampler Vials
Snap Top
Snap top autosampler vial
Snap Seal & Snap Ring
Autosampler Vials

Chrom Tech offers a comprehensive range of HPLC autosampler vials designed for compatibility with leading liquid chromatography and mass spectrometry systems. Available in clear, amber, or polymeric materials, these vials provide secure sealing, excellent sample recovery, and consistent analytical performance.

Most LC autosamplers use the standardized 12 × 32 mm format, with the 9 mm screw thread vial being the industry favorite. Its wide opening allows easy pipetting while maintaining compatibility with most autosampler tray designs. Snap top vials offer quick closure convenience, while crimp vials are preferred for highly volatile samples or tamper-evident storage.

Chrom Tech’s glass vials are made from Type I borosilicate for minimal reactivity and pH shift. For cost efficiency or chemical compatibility, we also supply plastic vials in polypropylene, polyethylene, and TPX—ideal for proteomic assays or limited-volume use. Both glass and plastic formats are offered in clear or light-protective amber and black finishes.

To support small-volume workflows, Chrom Tech carries limited-volume vials and pre-fitted vial inserts. When using wide-mouth vials, ensure the insert geometry matches the opening for correct alignment. We also stock GC vials and closures for gas chromatography applications.

Reduce costs without compromising quality—Chrom Tech’s HPLC vials, inserts, and closures deliver reliability, reproducibility, and immediate availability from our in-stock inventory. Contact Chrom Tech today for expert support or to request product recommendations.

Shop All Chromatography Vials
Explore screw thread, snap seal, crimp top, headspace, and specialty vials—all trusted and stocked by Chrom Tech.
Explore the Vials Brochure
View Chrom Tech’s complete vial selection, technical specifications, and compatibility guidance.
Key Definitions ▸
Autosampler Vial
A small container designed to hold analytical samples for automated injection into an HPLC or LC/MS system.
Wide Mouth Opening
A larger vial opening (typically 9 mm) that improves pipetting accuracy and reduces sample transfer errors.
Snap Top
A vial closure type that allows fast, tool-free sealing—ideal for high-throughput workflows.
Crimp Vial
A vial sealed with a metal crimp cap to maximize evaporation resistance and ensure tamper-evident closure.
Limited-Volume Vial
A vial designed to reduce dead volume and improve recovery for low-volume samples, often used with inserts.
Frequently Asked Questions ▸
What is the most common HPLC vial size?
The industry-standard 12 × 32 mm autosampler vial with a 9 mm screw thread opening is the most widely used format. It offers broad autosampler compatibility and straightforward capping for routine workflows.
Should I use glass or plastic HPLC vials?
Glass vials provide the highest chemical inertness and are recommended for most chromatographic applications. Plastic vials (polypropylene or TPX) are ideal when working with proteins, ultra-low-volume samples, or when eliminating potential interactions with glass is critical.
Are Chrom Tech vials compatible with all autosamplers?
Yes. Chrom Tech autosampler vials follow strict dimensional standards and are compatible with most major autosampler platforms, including Agilent, Thermo Fisher, Waters, Shimadzu, and additional OEM systems.