DB-5ms EVDX

DB-5ms EVDX column

Agilent DB-5ms EVDX GC Columns

Agilent J&W DB-5ms EVDX GC columns are engineered for high-confidence confirmatory analysis of drugs of abuse, providing exceptional selectivity, thermal stability, and MS-compatible performance for complex forensic toxicology workflows. Each column is individually configured and tested using a comprehensive drug confirmation mix containing caffeine, glutethimides, lidocaine, phenobarbital, EDDP, methaqualone, methadone, cocaine, desipramine, and carbamazepine—ensuring reliable retention behavior and peak shape consistency for these critical analytes.

With an operating temperature range of –60 Â°C to 325/350 Â°C, DB-5ms EVDX supports fast, efficient separations across a wide spectrum of volatile to semivolatile drug compounds. Its ultra-low bleed characteristics make it ideal for sensitive mass-spectrometric detection, reducing background noise and improving signal-to-noise ratios in demanding forensic applications.

Every DB-5ms EVDX column is manufactured and tested to Agilent’s stringent industry QC standards, ensuring batch-to-batch reproducibility and dependable analytical performance. Whether used for toxicology confirmations, drug screening, or complex impurity profiling, DB-5ms EVDX delivers the accuracy, stability, and ruggedness required for high-value forensic and clinical testing environments.

Key Definitions â–¸
DB-5ms EVDX
An Agilent GC column engineered for confirmatory analysis of drugs of abuse, featuring ultra-low bleed, MS-friendly performance, and consistent retention behavior for a wide range of volatile and semivolatile compounds.
Drug Confirmation Mix
A validated mixture of compounds—including caffeine, glutethimides, lidocaine, phenobarbital, EDDP, methaqualone, methadone, cocaine, desipramine, and carbamazepine— used to test and verify the column’s suitability for forensic toxicology workflows.
Ultra-Low Bleed
A performance characteristic indicating minimal release of stationary-phase material, resulting in cleaner baselines, reduced detector fouling, and improved sensitivity— especially important for MS-based drug confirmation.
EVDX Temperature Range
The DB-5ms EVDX operates from –60 Â°C to 325/350 Â°C, allowing analysis of both highly volatile and thermally stable drug compounds with consistent peak shape and retention across the full temperature span.
Frequently Asked Questions â–¸
What types of compounds are included in the DB-5ms EVDX test mix?
The test mix includes caffeine, glutethimides, lidocaine, phenobarbital, EDDP, methaqualone, methadone, cocaine, desipramine, and carbamazepine—representing a broad spectrum of analytes relevant to forensic drug confirmation workflows.
Why is DB-5ms EVDX recommended for confirmatory drug analysis?
DB-5ms EVDX provides ultra-low bleed and consistent retention, both of which are critical for sensitive MS detection and accurate identification of drugs of abuse, metabolites, and structurally related compounds.
What temperature range does the DB-5ms EVDX support?
The column operates from –60 Â°C to 325/350 Â°C, enabling analysis of everything from volatile drugs to thermally robust compounds, while maintaining sharp peak shapes throughout the analytical range.
Can DB-5ms EVDX be used for matrices other than forensic samples?
Yes. Its extended volatility range and MS-friendly performance make it suitable for pharmaceutical, environmental, and general toxicology applications requiring reliable analysis of volatile and semivolatile compounds.