DB-17ms Low-Bleed

DB-17ms Low-Bleed

DB-17ms Low Bleed GC/MS Columns

Agilent J&W DB-17ms is a mid-polarity GC/MS column engineered for low bleed, high inertness, and outstanding reproducibility across a wide range of applications. Built on a (50%-phenyl)-methylpolysiloxane stationary phase, DB-17ms provides significantly different selectivity than traditional non-polar phases, making it ideal for separating complex mixtures, resolving co-eluting compounds, and improving confidence in GC/MS identifications.

Its mid-polarity chemistry supports enhanced separation of pesticides, herbicides, semivolatile organic compounds (SVOCs), and multi-functional analytes encountered in environmental, food safety, forensics, and pharmaceutical workflows. DB-17ms maintains excellent inertness for active compounds—including acidic, basic, or adsorptive analytes—ensuring symmetrical peak shapes, improved recovery, and accurate quantitation at trace levels.

With its ultra-low bleed profile, DB-17ms provides cleaner baselines and high signal-to-noise ratios, enabling superior mass spectral integrity for sensitive GC/MS detection. The bonded and cross-linked design allows solvent rinsing and supports elevated temperature operation, giving the column durability and long service life even under demanding analytical conditions.

Whether used as a primary analytical column or paired with other phases for confirmation analysis, DB-17ms delivers robust, repeatable performance and complementary selectivity—making it a highly versatile choice for semivolatiles methods, pesticide residue analysis, and other mid-polarity-driven GC/MS workflows requiring precision and reliability.

Key Definitions â–¸
(50%-Phenyl)-Methylpolysiloxane Phase
A mid-polarity GC stationary phase consisting of 50% phenyl and 50% dimethylpolysiloxane. This chemistry provides enhanced separation for complex or multifunctional analytes compared to traditional 5% phenyl non-polar phases.
Mid-Polarity Selectivity
A balance of polar and non-polar interactions that improves resolution of structurally similar analytes. Mid-polarity columns like DB-17ms are ideal for pesticides, herbicides, SVOCs, and other analytes requiring complementary selectivity to non-polar columns.
Ultra Low Bleed
A performance characteristic describing the minimal release of stationary-phase material during analysis. Ultra low bleed yields cleaner baselines, improves mass spectral accuracy, and enhances sensitivity in GC/MS workflows.
Bonded and Cross-Linked
A rugged column manufacturing process where the stationary phase is chemically bonded to the inner surface of the capillary and further stabilized through cross-linking. This increases thermal stability, supports solvent rinsing, and improves long-term durability.
Semivolatiles (SVOCs)
Organic compounds with moderate vapor pressures commonly analyzed in environmental testing. DB-17ms provides strong inertness and distinctive mid-polarity separation ideal for SVOC confirmation and quantitation.
Frequently Asked Questions â–¸
What makes DB-17ms different from other mid-polarity GC columns?
DB-17ms is built on a (50%-phenyl)-methylpolysiloxane stationary phase that provides distinctive mid-polarity selectivity. Its combination of ultra-low bleed, strong inertness, and solvent-rinsable bonded phase offers more stable, reproducible performance for pesticides, herbicides, SVOCs, and multi-functional analytes compared to less robust mid-polar columns.
What types of applications benefit most from DB-17ms?
DB-17ms is ideal for pesticide residue analysis, environmental semivolatiles (SVOCs), pharmaceutical impurity profiling, forensic toxicology, food and fragrance analysis, and any workflow requiring complementary selectivity to non-polar 5-phase columns.
Is DB-17ms suitable as a confirmation column for GC/MS?
Yes. DB-17ms provides complementary selectivity to non-polar columns such as DB-5ms, making it an excellent confirmation column for pesticide, SVOC, and forensic workflows where multi-column verification is required for regulatory or confidence-building purposes.
Can DB-17ms operate at high oven temperatures?
Yes. The bonded and cross-linked phase provides strong thermal stability and supports extended high-temperature operation required for semivolatiles analysis and other high-boiling analytes. It also allows solvent rinsing to maintain long-term performance.
How does DB-17ms improve mass spectral quality in GC/MS?
DB-17ms has ultra-low bleed characteristics, reducing background noise and maintaining cleaner mass spectra. This improves signal-to-noise ratios and supports more accurate identification and quantitation, particularly for trace-level analytes.